Enzyme
Found in hops (Humulus lupulus). The enzyme can also methylate xanthogalenol.
OMT
Enzyme
Xanthohumol 4-O-methyltransferase
Enzyme name
EC:2.1.1.338
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:desmethylxanthohumol 6'-O-methyltransferase
Sysname
S-adenosyl-L-methionine + desmethylxanthohumol = S-adenosyl-L-homocysteine + xanthohumol [RN:R08004]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];xanthohumol [CPD:C16417]
Product
Species information
Lonicera japonica
Species name
Japanese honeysuckle (Lonicera japonica) is a species of eudicot in the family Caprifoliaceae (honeysuckle famly).
Species info
Gene sequence info
Lonicera_japonica.OMT.fa
Download
>Lj1C711G4.1
MSLNCAIKLGIPDAINNHGHPMTLSDLIDTLSINKKKSDGIHRLMRMLVHSGFFVEKDTPENGKEVGYWLTPASRLFLKDEPLCLTPFLQLMLDPVIKKPWHYMSEWFQNEDRTPFETAHGMTIWEYAGNRSKFNNLFNVAMASDARLIASVVVKDCGVIFEGLESVVDVGGGTGTSMRADRGVPAVEVHGA
>Lj1A733G57.1
MEKFEGEAMLKGQSQIWQYMFNFADSMALRCAVELRISDIIHSHGHPITLSQIAASIDSSSEVDISCLARILRVLVRNKIFTATLPSDSGDTVYGLTPSSMWLLHGAELTLAPMLLMETHQWLMSPWHQLSACVKEGGIAFEKAHGSEIWDFASNNPEFNRIFNDGMGCTAKIVTRAIISGYKDGFDCIGSLVDVGGGIGTVMIEIVKTYSHIKGINFDLPHVVATAPEYDGVSHVGGDMFKAIPKADAVFMKWILHDWNDEDCVKILKNCRKAIPEKTGKLIIAEVVLQPDGEGLFDNTGLAFDLLMIAHSSGGKERTEPEWKNYL
>Lj1A711T15.1
MFQAIPPANAVLLEWILHDWNDEECVKILKLSKEAIPSKEEGGKVIIIDMVVNYSNNQKKDDNSIETQLFFDMLMMVSLNGKERNEKEWAKLFKAAGFNGGFMITPILGLRSIIEVFP
>Lj1A710G32.1
MSLNCAINLGIPDAINNHGRPMTLSDLIDALPINKKKSYGIYRLMRMLVHSGYFVEKETPGNRQELGYWLTPASRLVLRDEPLSITPFLQLVLDPVIKKPWDYMSEWFQNEERTPFEMAHGMTMWEFAGHESKFNNLFNEAMASDARLIASVMVKDCGAVFEGLESIVDVGGGTGMVAKAVAGAYPELKCTVLDLPQVVGDLVGSENLKFVGGDMFEAIPPANAVLLKSILHDWNDEECVKILKLSKEAIPSKEEGGKVIIIDMVVNNCNNQKKDDNSMETQLFFDIAMMVLFTGKERTEKEWAKLFEAAAFNGGFKITHILGLRSVIEVFP
>Lj1A730G54.1
MEKFEGEAMLKGQSQIWQYMFNFADSMALRCAVELRISDIIHSHGHPITLSQIAASIDSSSEVDISCLARILRVLVRNKIFTATLPSDSGDTVYGLTPSSMWLLHGAELTLAPMLLMETHQWLMSPWHQLSACVKEGGIAFEKAHGSEIWDFASNNPEFNRIFNDGMGCTAKIVTRAIISGYKDGFDCIGSLVDVGGGIGTVMIEIVKTYSHIKGINFDLPHVVATAPEYDGVSHVGGDMFKAIPKADAVFMKWILHDWNDEDCVKILKNCRKAIPEKTGKLIIAEVVLQPDGEGLFDNTGLAFDLLMIAHSSGGKERTEPEWKKLLVDGGFPRYKIIKIPSLLSIIEAYPN
>Lj1C711G1.1
MEMTNSEQTGELLQAHAHIWNHILKFINTMSLNCAIKLGIPDAINNHGHPMTLSDLINTLPINKKKSDGIHRLMRMLVHSEFFVEKETPENGKEVGYWLTPASRLFLKDEPLCVTPFLQLMLDPVIKKPWHYMASVVVKDCGVIFEGLESVVDVGGGTGTLMRAVTTAFPQLKCTVLDLPQVVGDLVGSENLRFVGGDMFQAIPPANAVLLEE
>Lj1A710T38.1
MTNSEQTSELLHAHAHIWNHILNFINSMSLNCAIKLGIPDAINNHGHPMTLTELINALPINNKKSEGIHHLMRILIHSGYFIEKEIPENGQELGYWLTPASQLVLRNEPLSITPFLQLVLDPVFKKPWHYMSEWFQNEERTPFETAHGMTMWDYADHESKFNNLFNDAMASDAKLIASVVVEDCAAVFKGLKSIVDVGGGTGTMAKAVAGAYLELKYTVLDLPQVVGDLVGSENLKFVGGDMFEAIPPANAVLLKGWAWARARAQGELILHDWNDEECVKILKLSKEEGGKVIIIDMVVNNYNKQKKDDNSIETQLFFDMLMMVLFTGKERTEKEWAKLFKAAGFNGGFKISPILGLRSVIEVFP
>Lj1A710T37.1
MSLNCAIKLGIPDAINNHGSPMTLSELIDALPINNKKSDGIHRLMRMLVHSGYFVEKETPKNGQELGYWLTPASRLFLKDEPLCVTPFLRMIMDPVIKKPCHYMSEWFQNEALTPFEMAHGMTMWEYAGHESKFNNLFNDAMASDARLIASVVVNHCGAVFEGLESIVDVGGGTGTVAKVVAKAFPELKCTVLDLPQVVGDLVGCENLKFVGGDMFKAIPPANAVLLKWILHDWNDEVCVKILKQSKEAIPRKEEGGKVIIIDMVVNVGNNQKKDDNSIETQLFFDMLMMILLTGKERTEKEWAKLFKAAGFNGGFKITPILGLRSVIEVFP
>Lj8C107T0.1
MELINKGKKSSAISSELLQSQAHIWNHLFNFINSMSLKCAIQLNIPDIIHTHARPMTLSHLLQALAINTSKATHIYRLMRILTHSGFFTISKIQESGEENQEEGYLLTPACRLLLKDESTSVTPFLLAILDPALADPWHCMSRWFENEDKNAFETFHGRTLWDHMGSDERLCCLFNDAMASDAALIGRVDG
>Lj8A107T61.1
MMAKTVAGALPEVKWTVLDLPQVVAGLEGGKNLRFVSGDMFESIPNADAVLLKWILHDWNDEDCVKILKKCREAIPSKDEGGKVIIIEMIVDNRNPDKDSIENQFFFDMLMMVLATGRERNEKEWEKLFLDAGFSEHKITPLGLRSLIEVYP
>Lj9A402T71.1
MEGETKREAISEKEELAQAQLDVWKYIFGFTEMAVVKCAIDLGIPDALENKEGPTTLADLSSTLGCSPPALYRIMRFLMHRGIFKEKNTVEGHKGYVQTSLSGLLARSSKNSMADLVLLESSTVMLAPWLSLSSRVLATGTSAFEAANGQDIWRYAATNPNHCKLIDDAMACDARVAVPAIVESCSELFEGVGSLVDVGGGNATTLQLVVKYCPWIRGINYDLPHVVSVAPKYDGVEHVGGDMFDSVPKADAAFLKWVLHDWGDDECIQILKKCREAIPKEKGKVIIVEAIMEEEEENKYKDLGLTLDMVMMAHTNIGKERTLKEWAYVLSQAGFSRHTVKHIEAVQSVIVAYP
MSLNCAIKLGIPDAINNHGHPMTLSDLIDTLSINKKKSDGIHRLMRMLVHSGFFVEKDTPENGKEVGYWLTPASRLFLKDEPLCLTPFLQLMLDPVIKKPWHYMSEWFQNEDRTPFETAHGMTIWEYAGNRSKFNNLFNVAMASDARLIASVVVKDCGVIFEGLESVVDVGGGTGTSMRADRGVPAVEVHGA
>Lj1A733G57.1
MEKFEGEAMLKGQSQIWQYMFNFADSMALRCAVELRISDIIHSHGHPITLSQIAASIDSSSEVDISCLARILRVLVRNKIFTATLPSDSGDTVYGLTPSSMWLLHGAELTLAPMLLMETHQWLMSPWHQLSACVKEGGIAFEKAHGSEIWDFASNNPEFNRIFNDGMGCTAKIVTRAIISGYKDGFDCIGSLVDVGGGIGTVMIEIVKTYSHIKGINFDLPHVVATAPEYDGVSHVGGDMFKAIPKADAVFMKWILHDWNDEDCVKILKNCRKAIPEKTGKLIIAEVVLQPDGEGLFDNTGLAFDLLMIAHSSGGKERTEPEWKNYL
>Lj1A711T15.1
MFQAIPPANAVLLEWILHDWNDEECVKILKLSKEAIPSKEEGGKVIIIDMVVNYSNNQKKDDNSIETQLFFDMLMMVSLNGKERNEKEWAKLFKAAGFNGGFMITPILGLRSIIEVFP
>Lj1A710G32.1
MSLNCAINLGIPDAINNHGRPMTLSDLIDALPINKKKSYGIYRLMRMLVHSGYFVEKETPGNRQELGYWLTPASRLVLRDEPLSITPFLQLVLDPVIKKPWDYMSEWFQNEERTPFEMAHGMTMWEFAGHESKFNNLFNEAMASDARLIASVMVKDCGAVFEGLESIVDVGGGTGMVAKAVAGAYPELKCTVLDLPQVVGDLVGSENLKFVGGDMFEAIPPANAVLLKSILHDWNDEECVKILKLSKEAIPSKEEGGKVIIIDMVVNNCNNQKKDDNSMETQLFFDIAMMVLFTGKERTEKEWAKLFEAAAFNGGFKITHILGLRSVIEVFP
>Lj1A730G54.1
MEKFEGEAMLKGQSQIWQYMFNFADSMALRCAVELRISDIIHSHGHPITLSQIAASIDSSSEVDISCLARILRVLVRNKIFTATLPSDSGDTVYGLTPSSMWLLHGAELTLAPMLLMETHQWLMSPWHQLSACVKEGGIAFEKAHGSEIWDFASNNPEFNRIFNDGMGCTAKIVTRAIISGYKDGFDCIGSLVDVGGGIGTVMIEIVKTYSHIKGINFDLPHVVATAPEYDGVSHVGGDMFKAIPKADAVFMKWILHDWNDEDCVKILKNCRKAIPEKTGKLIIAEVVLQPDGEGLFDNTGLAFDLLMIAHSSGGKERTEPEWKKLLVDGGFPRYKIIKIPSLLSIIEAYPN
>Lj1C711G1.1
MEMTNSEQTGELLQAHAHIWNHILKFINTMSLNCAIKLGIPDAINNHGHPMTLSDLINTLPINKKKSDGIHRLMRMLVHSEFFVEKETPENGKEVGYWLTPASRLFLKDEPLCVTPFLQLMLDPVIKKPWHYMASVVVKDCGVIFEGLESVVDVGGGTGTLMRAVTTAFPQLKCTVLDLPQVVGDLVGSENLRFVGGDMFQAIPPANAVLLEE
>Lj1A710T38.1
MTNSEQTSELLHAHAHIWNHILNFINSMSLNCAIKLGIPDAINNHGHPMTLTELINALPINNKKSEGIHHLMRILIHSGYFIEKEIPENGQELGYWLTPASQLVLRNEPLSITPFLQLVLDPVFKKPWHYMSEWFQNEERTPFETAHGMTMWDYADHESKFNNLFNDAMASDAKLIASVVVEDCAAVFKGLKSIVDVGGGTGTMAKAVAGAYLELKYTVLDLPQVVGDLVGSENLKFVGGDMFEAIPPANAVLLKGWAWARARAQGELILHDWNDEECVKILKLSKEEGGKVIIIDMVVNNYNKQKKDDNSIETQLFFDMLMMVLFTGKERTEKEWAKLFKAAGFNGGFKISPILGLRSVIEVFP
>Lj1A710T37.1
MSLNCAIKLGIPDAINNHGSPMTLSELIDALPINNKKSDGIHRLMRMLVHSGYFVEKETPKNGQELGYWLTPASRLFLKDEPLCVTPFLRMIMDPVIKKPCHYMSEWFQNEALTPFEMAHGMTMWEYAGHESKFNNLFNDAMASDARLIASVVVNHCGAVFEGLESIVDVGGGTGTVAKVVAKAFPELKCTVLDLPQVVGDLVGCENLKFVGGDMFKAIPPANAVLLKWILHDWNDEVCVKILKQSKEAIPRKEEGGKVIIIDMVVNVGNNQKKDDNSIETQLFFDMLMMILLTGKERTEKEWAKLFKAAGFNGGFKITPILGLRSVIEVFP
>Lj8C107T0.1
MELINKGKKSSAISSELLQSQAHIWNHLFNFINSMSLKCAIQLNIPDIIHTHARPMTLSHLLQALAINTSKATHIYRLMRILTHSGFFTISKIQESGEENQEEGYLLTPACRLLLKDESTSVTPFLLAILDPALADPWHCMSRWFENEDKNAFETFHGRTLWDHMGSDERLCCLFNDAMASDAALIGRVDG
>Lj8A107T61.1
MMAKTVAGALPEVKWTVLDLPQVVAGLEGGKNLRFVSGDMFESIPNADAVLLKWILHDWNDEDCVKILKKCREAIPSKDEGGKVIIIEMIVDNRNPDKDSIENQFFFDMLMMVLATGRERNEKEWEKLFLDAGFSEHKITPLGLRSLIEVYP
>Lj9A402T71.1
MEGETKREAISEKEELAQAQLDVWKYIFGFTEMAVVKCAIDLGIPDALENKEGPTTLADLSSTLGCSPPALYRIMRFLMHRGIFKEKNTVEGHKGYVQTSLSGLLARSSKNSMADLVLLESSTVMLAPWLSLSSRVLATGTSAFEAANGQDIWRYAATNPNHCKLIDDAMACDARVAVPAIVESCSELFEGVGSLVDVGGGNATTLQLVVKYCPWIRGINYDLPHVVSVAPKYDGVEHVGGDMFDSVPKADAAFLKWVLHDWGDDECIQILKKCREAIPKEKGKVIIVEAIMEEEEENKYKDLGLTLDMVMMAHTNIGKERTLKEWAYVLSQAGFSRHTVKHIEAVQSVIVAYP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University