Enzyme
The enzyme catalyses the biosynthesis of pterostilbene from resveratrol.
ROMT
Enzyme
Trans-resveratrol di-O-methyltransferase
Enzyme name
EC:2.1.1.240
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:trans-resveratrol 3,5-O-dimethyltransferase
Sysname
2 S-adenosyl-L-methionine + trans-resveratrol = 2 S-adenosyl-L-homocysteine + pterostilbene (overall reaction) [RN:R09872];(1a) S-adenosyl-L-methionine + trans-resveratrol = S-adenosyl-L-homocysteine + 3-methoxy-4',5-dihydroxy-trans-stilbene [RN:R09870];(1b) S-adenosyl-L-methionine + 3-methoxy-4',5-dihydroxy-trans-stilbene = S-adenosyl-L-homocysteine + pterostilbene [RN:R09871]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];pterostilbene [CPD:C10287];3-methoxy-4',5-dihydroxy-trans-stilbene [CPD:C20154]
Product
Species information
Lonicera japonica
Species name
Japanese honeysuckle (Lonicera japonica) is a species of eudicot in the family Caprifoliaceae (honeysuckle famly).
Species info
Gene sequence info
Lonicera_japonica.ROMT.fa
Download
>Lj1C711G4.1
MSLNCAIKLGIPDAINNHGHPMTLSDLIDTLSINKKKSDGIHRLMRMLVHSGFFVEKDTPENGKEVGYWLTPASRLFLKDEPLCLTPFLQLMLDPVIKKPWHYMSEWFQNEDRTPFETAHGMTIWEYAGNRSKFNNLFNVAMASDARLIASVVVKDCGVIFEGLESVVDVGGGTGTSMRADRGVPAVEVHGA
>Lj1A711T15.1
MFQAIPPANAVLLEWILHDWNDEECVKILKLSKEAIPSKEEGGKVIIIDMVVNYSNNQKKDDNSIETQLFFDMLMMVSLNGKERNEKEWAKLFKAAGFNGGFMITPILGLRSIIEVFP
>Lj1A710G32.1
MSLNCAINLGIPDAINNHGRPMTLSDLIDALPINKKKSYGIYRLMRMLVHSGYFVEKETPGNRQELGYWLTPASRLVLRDEPLSITPFLQLVLDPVIKKPWDYMSEWFQNEERTPFEMAHGMTMWEFAGHESKFNNLFNEAMASDARLIASVMVKDCGAVFEGLESIVDVGGGTGMVAKAVAGAYPELKCTVLDLPQVVGDLVGSENLKFVGGDMFEAIPPANAVLLKSILHDWNDEECVKILKLSKEAIPSKEEGGKVIIIDMVVNNCNNQKKDDNSMETQLFFDIAMMVLFTGKERTEKEWAKLFEAAAFNGGFKITHILGLRSVIEVFP
>Lj1A711G15.1
MLMMVSLNGKERNEKEWANLFNAAGFNGGFMITPILGLRSIIETNSEFFSLWILHDWNDEDQCVKIIKLSEEAIPSKEEGGMVIIIEMALNNCNNQKKNDNSVETQLLHVRLVPAAVFFVSLHSQAGNLLGSEHLRFVGGDMFVAIPPANAALLKSILHDWNDEECAKILKQSKEEGGKEIFIDMVVNYSNSQKKDDNSVETQLLIDMLMMVSVNGKERNQKNGQSSSRLLPSMVVLSLFLFLV
>Lj1C711G1.1
MEMTNSEQTGELLQAHAHIWNHILKFINTMSLNCAIKLGIPDAINNHGHPMTLSDLINTLPINKKKSDGIHRLMRMLVHSEFFVEKETPENGKEVGYWLTPASRLFLKDEPLCVTPFLQLMLDPVIKKPWHYMASVVVKDCGVIFEGLESVVDVGGGTGTLMRAVTTAFPQLKCTVLDLPQVVGDLVGSENLRFVGGDMFQAIPPANAVLLEE
>Lj1A710T38.1
MTNSEQTSELLHAHAHIWNHILNFINSMSLNCAIKLGIPDAINNHGHPMTLTELINALPINNKKSEGIHHLMRILIHSGYFIEKEIPENGQELGYWLTPASQLVLRNEPLSITPFLQLVLDPVFKKPWHYMSEWFQNEERTPFETAHGMTMWDYADHESKFNNLFNDAMASDAKLIASVVVEDCAAVFKGLKSIVDVGGGTGTMAKAVAGAYLELKYTVLDLPQVVGDLVGSENLKFVGGDMFEAIPPANAVLLKGWAWARARAQGELILHDWNDEECVKILKLSKEEGGKVIIIDMVVNNYNKQKKDDNSIETQLFFDMLMMVLFTGKERTEKEWAKLFKAAGFNGGFKISPILGLRSVIEVFP
>Lj1A710T37.1
MSLNCAIKLGIPDAINNHGSPMTLSELIDALPINNKKSDGIHRLMRMLVHSGYFVEKETPKNGQELGYWLTPASRLFLKDEPLCVTPFLRMIMDPVIKKPCHYMSEWFQNEALTPFEMAHGMTMWEYAGHESKFNNLFNDAMASDARLIASVVVNHCGAVFEGLESIVDVGGGTGTVAKVVAKAFPELKCTVLDLPQVVGDLVGCENLKFVGGDMFKAIPPANAVLLKWILHDWNDEVCVKILKQSKEAIPRKEEGGKVIIIDMVVNVGNNQKKDDNSIETQLFFDMLMMILLTGKERTEKEWAKLFKAAGFNGGFKITPILGLRSVIEVFP
>Lj8C107T0.1
MELINKGKKSSAISSELLQSQAHIWNHLFNFINSMSLKCAIQLNIPDIIHTHARPMTLSHLLQALAINTSKATHIYRLMRILTHSGFFTISKIQESGEENQEEGYLLTPACRLLLKDESTSVTPFLLAILDPALADPWHCMSRWFENEDKNAFETFHGRTLWDHMGSDERLCCLFNDAMASDAALIGRVDG
>Lj8A107T61.1
MMAKTVAGALPEVKWTVLDLPQVVAGLEGGKNLRFVSGDMFESIPNADAVLLKWILHDWNDEDCVKILKKCREAIPSKDEGGKVIIIEMIVDNRNPDKDSIENQFFFDMLMMVLATGRERNEKEWEKLFLDAGFSEHKITPLGLRSLIEVYP
MSLNCAIKLGIPDAINNHGHPMTLSDLIDTLSINKKKSDGIHRLMRMLVHSGFFVEKDTPENGKEVGYWLTPASRLFLKDEPLCLTPFLQLMLDPVIKKPWHYMSEWFQNEDRTPFETAHGMTIWEYAGNRSKFNNLFNVAMASDARLIASVVVKDCGVIFEGLESVVDVGGGTGTSMRADRGVPAVEVHGA
>Lj1A711T15.1
MFQAIPPANAVLLEWILHDWNDEECVKILKLSKEAIPSKEEGGKVIIIDMVVNYSNNQKKDDNSIETQLFFDMLMMVSLNGKERNEKEWAKLFKAAGFNGGFMITPILGLRSIIEVFP
>Lj1A710G32.1
MSLNCAINLGIPDAINNHGRPMTLSDLIDALPINKKKSYGIYRLMRMLVHSGYFVEKETPGNRQELGYWLTPASRLVLRDEPLSITPFLQLVLDPVIKKPWDYMSEWFQNEERTPFEMAHGMTMWEFAGHESKFNNLFNEAMASDARLIASVMVKDCGAVFEGLESIVDVGGGTGMVAKAVAGAYPELKCTVLDLPQVVGDLVGSENLKFVGGDMFEAIPPANAVLLKSILHDWNDEECVKILKLSKEAIPSKEEGGKVIIIDMVVNNCNNQKKDDNSMETQLFFDIAMMVLFTGKERTEKEWAKLFEAAAFNGGFKITHILGLRSVIEVFP
>Lj1A711G15.1
MLMMVSLNGKERNEKEWANLFNAAGFNGGFMITPILGLRSIIETNSEFFSLWILHDWNDEDQCVKIIKLSEEAIPSKEEGGMVIIIEMALNNCNNQKKNDNSVETQLLHVRLVPAAVFFVSLHSQAGNLLGSEHLRFVGGDMFVAIPPANAALLKSILHDWNDEECAKILKQSKEEGGKEIFIDMVVNYSNSQKKDDNSVETQLLIDMLMMVSVNGKERNQKNGQSSSRLLPSMVVLSLFLFLV
>Lj1C711G1.1
MEMTNSEQTGELLQAHAHIWNHILKFINTMSLNCAIKLGIPDAINNHGHPMTLSDLINTLPINKKKSDGIHRLMRMLVHSEFFVEKETPENGKEVGYWLTPASRLFLKDEPLCVTPFLQLMLDPVIKKPWHYMASVVVKDCGVIFEGLESVVDVGGGTGTLMRAVTTAFPQLKCTVLDLPQVVGDLVGSENLRFVGGDMFQAIPPANAVLLEE
>Lj1A710T38.1
MTNSEQTSELLHAHAHIWNHILNFINSMSLNCAIKLGIPDAINNHGHPMTLTELINALPINNKKSEGIHHLMRILIHSGYFIEKEIPENGQELGYWLTPASQLVLRNEPLSITPFLQLVLDPVFKKPWHYMSEWFQNEERTPFETAHGMTMWDYADHESKFNNLFNDAMASDAKLIASVVVEDCAAVFKGLKSIVDVGGGTGTMAKAVAGAYLELKYTVLDLPQVVGDLVGSENLKFVGGDMFEAIPPANAVLLKGWAWARARAQGELILHDWNDEECVKILKLSKEEGGKVIIIDMVVNNYNKQKKDDNSIETQLFFDMLMMVLFTGKERTEKEWAKLFKAAGFNGGFKISPILGLRSVIEVFP
>Lj1A710T37.1
MSLNCAIKLGIPDAINNHGSPMTLSELIDALPINNKKSDGIHRLMRMLVHSGYFVEKETPKNGQELGYWLTPASRLFLKDEPLCVTPFLRMIMDPVIKKPCHYMSEWFQNEALTPFEMAHGMTMWEYAGHESKFNNLFNDAMASDARLIASVVVNHCGAVFEGLESIVDVGGGTGTVAKVVAKAFPELKCTVLDLPQVVGDLVGCENLKFVGGDMFKAIPPANAVLLKWILHDWNDEVCVKILKQSKEAIPRKEEGGKVIIIDMVVNVGNNQKKDDNSIETQLFFDMLMMILLTGKERTEKEWAKLFKAAGFNGGFKITPILGLRSVIEVFP
>Lj8C107T0.1
MELINKGKKSSAISSELLQSQAHIWNHLFNFINSMSLKCAIQLNIPDIIHTHARPMTLSHLLQALAINTSKATHIYRLMRILTHSGFFTISKIQESGEENQEEGYLLTPACRLLLKDESTSVTPFLLAILDPALADPWHCMSRWFENEDKNAFETFHGRTLWDHMGSDERLCCLFNDAMASDAALIGRVDG
>Lj8A107T61.1
MMAKTVAGALPEVKWTVLDLPQVVAGLEGGKNLRFVSGDMFESIPNADAVLLKWILHDWNDEDCVKILKKCREAIPSKDEGGKVIIIEMIVDNRNPDKDSIENQFFFDMLMMVLATGRERNEKEWEKLFLDAGFSEHKITPLGLRSLIEVYP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University