Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Lonicera japonica
Species name
Japanese honeysuckle (Lonicera japonica) is a species of eudicot in the family Caprifoliaceae (honeysuckle famly).
Species info
Gene sequence info
Lonicera_japonica.CHS.fa
Download
>Lj3A580T66.1
MVTVEEIRKAQRAEGPATILAIGTATPTHCVDQSTYPDYYFRITNSEHKVELKEKFKRMCEKSMIKKRYMHITEEILRENPSMCEYMAPSLDARQDIVVVEVPKLGKEAATRAIKEWGQPKSKITHLVFCTTSGIDMPGADYQLTKLLGLSPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIIGSDPVADVEKPLFEVVSAAQTILPDSDGAIDGHVREVGLTFHLLKDVPGIISKNIEKSLVEAFKPLGISDWNSLFWIAHPGGPAILDQVEEKLALKPKKLEATRHVLSEYGNMSSACVLFIMDEMRKKSGTDGFKTTGEGLEWGVLFGFGPGLTVETVVLHSLST
>Lj5C185T17.1
MGSGEMIMQEIKKASIGKATILALGKAFPHQLVMQEYLVDGYFKNTNCDDIVLKQKLARLFKTRYVVMSDKILNKYPELALEGSRVLLATSETTIIGFKPPSHDRPYDLVGVVLFGAGAGAKAVIVGLDPLVIERPLSEIHSAVQHFLPDTETIIDGQLTEEGISFKIGRELPQIIEDNIVDFCGMLVEGVGHSEKDYNKMFWVVHPGGPAILKWLEKKLDLLLGKLSASR
>Lj6A615G84.1
PPLQASDKTIFIQIFALEKMVTVEDVRKSQRAEGPAAVLAIGTATPTHCVDQSTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPSICEYMAPSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADFQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNTGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIIGSDPVLGIERPLFELVSASQTILPDSDGAIDGHLREVGLTFHLLKDVPVLISKNIEKSLVEAFKPLGISDWNSLFWIAHPGGPAILDQVEEKLALKPEKLGATRHVLSEYGNMSSACVLFIMDEMRKKSVKEGLETTGEGLEWGVLFGFGPGLTVETVVLHGLAT
>Lj6C717T25.1
MVTVEEVRNAQRAQGPATVMAIGTATPANCVDQSDYPDFYFRITNSEHRTELKEKFKRMCEKSTIKKRYMHLTEEILKEKPDMCAYMAPSLDARQDIVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRSSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAMIIGSDPMPEVEKPLFELLISKNIEKSLVEAFKPLGISDWNSIFWIAHPGGPAILDQVEKKLALKPEKMGATRHVLSEYGNMSSACVLFIMDEMRKKSANEGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVST
>Lj6A712T57.1
MVTVEEVRNAQRAQGPATVMAIGTATPANCVDQSDYPDFYFRITNSEHRTELKEKFKRMCEKSTIKKRYMHLTEEILKEQPDMCAYMAPSLDARQDIVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRSSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAMIIGSDPMPEVEKPLFELVSASQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFKPLGISDWNSIFWIAHPGGPAILDQVEKKLALKPEKMGATRHVLSEYGNMSSACVLFIMDEMRKKSANEGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVST
>Lj7C618G13.1
MGSVTVEEIRKAQRAQGPATVLAIGTATPANCVYQADYPDFYFRITKSEHKAELKEKFKRMCEKSMIRKRYMHLNEEILKENPGICEYMAPSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNAGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIIGADPDKSVERPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLKEAFAPIGITDWNSLFWIAHPGGPAILDQVEIKLGLKEEKLRPTRHVLSEYGNMSSACVLFILDELRKKSIEEGKATTGDGLEWGVLFGFGPGLTVETVVLHSVPASI
>Lj9A389T65.1
MGSGEMFLISKQGKTGGKATILALGKAFPHQLVMQEFLVDGYFKNTNCDDPVLKQNCNLDFFFGQYTGKTTTVKTRYVVMSDEILNKYPELTIEGHPTVTQRLDICNKAVTQMAIEASQSCINKWGRPISDITHLVYVSSSEARLPGGDLHLAKGLGLSPETNRVMLYFMGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSIDRPYDLVGVALFGDGAGATIIGDYNNLFWAVHPGGPAILNRVEKKLELLPEKLRASRRALADYGNASSNTIVYVLEYIMEENLKVKGEGDPEWGLILAFGPGITFEGILTRKLV
>Lj9A561T45.1
MSAHIINKDGSFDHQQHPSDLKSRARRVPTPGKATVLAMGKAFPSQLIPQDCLVEGYFRDTKCQDLSMKEKLERLCKTTTVKMRYTVMSREILDKYPELTIEGSSTIKQRLEIANPAVVEMAKQASIACIQEWGRSASEITHVVYVSSSEIRLPGGDLYLATELGLKNDVGRVMLYFLGCYGGSTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKERPYDLVGAALFGDGAAALIIGANPKPEESPFMELSHAVQQFLSGTNNVIDGQLTEEGINFKLGRDLPQKIEDNIEEFCSKLMEKSGVRDYNELFWAIHPGGPAILNRLESKLGLRSEKLECSRRALMDFGNVSSNTIFYVMEYMREELIKKDNGEEWGLGLAFGPGITFEGILLRSL
MVTVEEIRKAQRAEGPATILAIGTATPTHCVDQSTYPDYYFRITNSEHKVELKEKFKRMCEKSMIKKRYMHITEEILRENPSMCEYMAPSLDARQDIVVVEVPKLGKEAATRAIKEWGQPKSKITHLVFCTTSGIDMPGADYQLTKLLGLSPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIIGSDPVADVEKPLFEVVSAAQTILPDSDGAIDGHVREVGLTFHLLKDVPGIISKNIEKSLVEAFKPLGISDWNSLFWIAHPGGPAILDQVEEKLALKPKKLEATRHVLSEYGNMSSACVLFIMDEMRKKSGTDGFKTTGEGLEWGVLFGFGPGLTVETVVLHSLST
>Lj5C185T17.1
MGSGEMIMQEIKKASIGKATILALGKAFPHQLVMQEYLVDGYFKNTNCDDIVLKQKLARLFKTRYVVMSDKILNKYPELALEGSRVLLATSETTIIGFKPPSHDRPYDLVGVVLFGAGAGAKAVIVGLDPLVIERPLSEIHSAVQHFLPDTETIIDGQLTEEGISFKIGRELPQIIEDNIVDFCGMLVEGVGHSEKDYNKMFWVVHPGGPAILKWLEKKLDLLLGKLSASR
>Lj6A615G84.1
PPLQASDKTIFIQIFALEKMVTVEDVRKSQRAEGPAAVLAIGTATPTHCVDQSTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPSICEYMAPSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADFQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNTGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIIGSDPVLGIERPLFELVSASQTILPDSDGAIDGHLREVGLTFHLLKDVPVLISKNIEKSLVEAFKPLGISDWNSLFWIAHPGGPAILDQVEEKLALKPEKLGATRHVLSEYGNMSSACVLFIMDEMRKKSVKEGLETTGEGLEWGVLFGFGPGLTVETVVLHGLAT
>Lj6C717T25.1
MVTVEEVRNAQRAQGPATVMAIGTATPANCVDQSDYPDFYFRITNSEHRTELKEKFKRMCEKSTIKKRYMHLTEEILKEKPDMCAYMAPSLDARQDIVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRSSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAMIIGSDPMPEVEKPLFELLISKNIEKSLVEAFKPLGISDWNSIFWIAHPGGPAILDQVEKKLALKPEKMGATRHVLSEYGNMSSACVLFIMDEMRKKSANEGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVST
>Lj6A712T57.1
MVTVEEVRNAQRAQGPATVMAIGTATPANCVDQSDYPDFYFRITNSEHRTELKEKFKRMCEKSTIKKRYMHLTEEILKEQPDMCAYMAPSLDARQDIVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRSSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAMIIGSDPMPEVEKPLFELVSASQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFKPLGISDWNSIFWIAHPGGPAILDQVEKKLALKPEKMGATRHVLSEYGNMSSACVLFIMDEMRKKSANEGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVST
>Lj7C618G13.1
MGSVTVEEIRKAQRAQGPATVLAIGTATPANCVYQADYPDFYFRITKSEHKAELKEKFKRMCEKSMIRKRYMHLNEEILKENPGICEYMAPSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNAGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIIGADPDKSVERPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLKEAFAPIGITDWNSLFWIAHPGGPAILDQVEIKLGLKEEKLRPTRHVLSEYGNMSSACVLFILDELRKKSIEEGKATTGDGLEWGVLFGFGPGLTVETVVLHSVPASI
>Lj9A389T65.1
MGSGEMFLISKQGKTGGKATILALGKAFPHQLVMQEFLVDGYFKNTNCDDPVLKQNCNLDFFFGQYTGKTTTVKTRYVVMSDEILNKYPELTIEGHPTVTQRLDICNKAVTQMAIEASQSCINKWGRPISDITHLVYVSSSEARLPGGDLHLAKGLGLSPETNRVMLYFMGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSIDRPYDLVGVALFGDGAGATIIGDYNNLFWAVHPGGPAILNRVEKKLELLPEKLRASRRALADYGNASSNTIVYVLEYIMEENLKVKGEGDPEWGLILAFGPGITFEGILTRKLV
>Lj9A561T45.1
MSAHIINKDGSFDHQQHPSDLKSRARRVPTPGKATVLAMGKAFPSQLIPQDCLVEGYFRDTKCQDLSMKEKLERLCKTTTVKMRYTVMSREILDKYPELTIEGSSTIKQRLEIANPAVVEMAKQASIACIQEWGRSASEITHVVYVSSSEIRLPGGDLYLATELGLKNDVGRVMLYFLGCYGGSTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKERPYDLVGAALFGDGAAALIIGANPKPEESPFMELSHAVQQFLSGTNNVIDGQLTEEGINFKLGRDLPQKIEDNIEEFCSKLMEKSGVRDYNELFWAIHPGGPAILNRLESKLGLRSEKLECSRRALMDFGNVSSNTIFYVMEYMREELIKKDNGEEWGLGLAFGPGITFEGILLRSL
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University