Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Lonicera japonica
Species name
Japanese honeysuckle (Lonicera japonica) is a species of eudicot in the family Caprifoliaceae (honeysuckle famly).
Species info
Gene sequence info
Lonicera_japonica.4CL.fa
Download
>Lj1C211G2.1
MEKSGYGRDGIYRSLRPKILFPKDPNLSMITFLLRNISSYPHKPALIDADSNQTLNFAEFKSTLSKVSIGLQKLGVRKNDVVLIFAPNSIQFPLCFFGIIALGAIATTVNPAYTVAEISKQVKDCKPKMVITVGDLWEKVKGELVNSAGSVSNLPKVSIKQSDTAALLYSSGTTGVSKGVVLSHGNFIAAALMVTSDQEFAGEMHNLFLCVLPMFHVFGLAVILYSQLQRGNGVVSMGKFDFVMILKSIEKFRVTHMWVVPPIILALAKQSVVKKFDLSSLKQIGSGAAPLGKELMENCATNFPHAIVCQGYGMTETCGIVSVENSYGGTRHSGSTGTLAPGVESQIVSVDTVKPLPPKQLGEIWVRGPNMMQGYLNNPQATKLTIDKQGWVHTGDLGYFDEEGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPAAYVVRSPSSSLTEEDVQKFIAEQVAPFKRLRRVTFINTVPKSASGKILRRELIEKVRSKL
>Lj3P372T6.1
KVLGSIGRPLRHTEIKVVDVETDEVLPPGSKGIVKARGPQVMKGYYKNPSTTKQVLDEDGWLNTGDIGWIAPHHSVGRIVILEALFFLKVVPRIL
>Lj5A84G46.1
METKQEIIFRSKLPDIYIPTHLPLHSYCFQNISKFSSRPCLINGATGEIHTYADVELTARKVAAGLNKQGVKQGDTIMILLPNSPEFFFTFLGASYRGALSTMANPFFTPAEVVKQAKASNAKLIVTQSSYVDKVKDFASETGVKIVCIDSAPEGCLHFSELSSADESEMPEVEINPEDVVALPYSSGTTGLPKGVMLTHKGCVASVAQQVDGENPNLFMNCEDVMMCVLPLFHIYSLNISLCGVRVGAAILIMQKFDIVPFLELIQKYKVSIGPVVPPIVLAIAKSPIVDNYDMSSMRTMMSGAAPLGKELEDAVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAVMKIVDPETGASLPRHQSGEICIRGDQIMKGYLNDPKSTELTIDKEGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLLNHPNISDAAVVPMKEESAGEVPVAFVVRSGNSNITEDEIKQFISKQVVFYKRIKRVFFLDAIPKAPSGKILRKDLRARLAAGVPA
>Lj6A827T50.1
MALEVEEHVFRSKYAPVPVPDNLTLPDFVLQGSEFYANKVAFVESLTGKEYTHGQVVKETGRFAKALRSLGLKKGHVVVVVLPNIAEYPIVALGIMAAGGIFSGSNPSAHASEIKKQVEAKELGLPLIVLGEERVEGTMYWKELLEAGDRLSENIMNETVHQTDLCALPFSSGTTGLSKGVMLTHRNLVANLCSTLFSVGPELIGQVTTLGLIPFFHIYGLTGICCATLRNKGKVVVMGRYDLKAFLNALIAHEVTFAPIVPPIILGLVKDPIVNEFDLTKLKLRSIMTAAAPLAPEIQSEFEKKFPGVEVQEAYGMTEHSCITLTHGDPNKGHGIAKRQSVGFILPNLEVKFIDPDTGRSLPKNTPGEICVRSQCVMRGYYKNENETAHTIDENGWLHTGDIGYIDDDGDMFLVDRIKELIKYKGFQVAPAELEGILLTHPSIEDAAVMGYPQLNSTQLN*LILIIRM*INK*MSRAPTFFNFLACRIPDQEAGEIPGACVVMSPEGKESEEEIIKYVASNVAHYKRVRVLQFVDTIPKSPSGKIMRRLLRDKMLQNMNSSRTTQNHNS
MEKSGYGRDGIYRSLRPKILFPKDPNLSMITFLLRNISSYPHKPALIDADSNQTLNFAEFKSTLSKVSIGLQKLGVRKNDVVLIFAPNSIQFPLCFFGIIALGAIATTVNPAYTVAEISKQVKDCKPKMVITVGDLWEKVKGELVNSAGSVSNLPKVSIKQSDTAALLYSSGTTGVSKGVVLSHGNFIAAALMVTSDQEFAGEMHNLFLCVLPMFHVFGLAVILYSQLQRGNGVVSMGKFDFVMILKSIEKFRVTHMWVVPPIILALAKQSVVKKFDLSSLKQIGSGAAPLGKELMENCATNFPHAIVCQGYGMTETCGIVSVENSYGGTRHSGSTGTLAPGVESQIVSVDTVKPLPPKQLGEIWVRGPNMMQGYLNNPQATKLTIDKQGWVHTGDLGYFDEEGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPAAYVVRSPSSSLTEEDVQKFIAEQVAPFKRLRRVTFINTVPKSASGKILRRELIEKVRSKL
>Lj3P372T6.1
KVLGSIGRPLRHTEIKVVDVETDEVLPPGSKGIVKARGPQVMKGYYKNPSTTKQVLDEDGWLNTGDIGWIAPHHSVGRIVILEALFFLKVVPRIL
>Lj5A84G46.1
METKQEIIFRSKLPDIYIPTHLPLHSYCFQNISKFSSRPCLINGATGEIHTYADVELTARKVAAGLNKQGVKQGDTIMILLPNSPEFFFTFLGASYRGALSTMANPFFTPAEVVKQAKASNAKLIVTQSSYVDKVKDFASETGVKIVCIDSAPEGCLHFSELSSADESEMPEVEINPEDVVALPYSSGTTGLPKGVMLTHKGCVASVAQQVDGENPNLFMNCEDVMMCVLPLFHIYSLNISLCGVRVGAAILIMQKFDIVPFLELIQKYKVSIGPVVPPIVLAIAKSPIVDNYDMSSMRTMMSGAAPLGKELEDAVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAVMKIVDPETGASLPRHQSGEICIRGDQIMKGYLNDPKSTELTIDKEGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLLNHPNISDAAVVPMKEESAGEVPVAFVVRSGNSNITEDEIKQFISKQVVFYKRIKRVFFLDAIPKAPSGKILRKDLRARLAAGVPA
>Lj6A827T50.1
MALEVEEHVFRSKYAPVPVPDNLTLPDFVLQGSEFYANKVAFVESLTGKEYTHGQVVKETGRFAKALRSLGLKKGHVVVVVLPNIAEYPIVALGIMAAGGIFSGSNPSAHASEIKKQVEAKELGLPLIVLGEERVEGTMYWKELLEAGDRLSENIMNETVHQTDLCALPFSSGTTGLSKGVMLTHRNLVANLCSTLFSVGPELIGQVTTLGLIPFFHIYGLTGICCATLRNKGKVVVMGRYDLKAFLNALIAHEVTFAPIVPPIILGLVKDPIVNEFDLTKLKLRSIMTAAAPLAPEIQSEFEKKFPGVEVQEAYGMTEHSCITLTHGDPNKGHGIAKRQSVGFILPNLEVKFIDPDTGRSLPKNTPGEICVRSQCVMRGYYKNENETAHTIDENGWLHTGDIGYIDDDGDMFLVDRIKELIKYKGFQVAPAELEGILLTHPSIEDAAVMGYPQLNSTQLN*LILIIRM*INK*MSRAPTFFNFLACRIPDQEAGEIPGACVVMSPEGKESEEEIIKYVASNVAHYKRVRVLQFVDTIPKSPSGKIMRRLLRDKMLQNMNSSRTTQNHNS
Sheng jun & Dong yang Teams, Yunnan agriculture University