Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Lobularia maritima
Species name
Sweet alyssum (Lobularia maritima) is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Lobularia_maritima.HIDH.fa
Download
>Spe01352.t1
MDPDSEIAYDYPRYRVYKSGRIERLVTETFVPPSLNLENDVVSTDAVYSPEKNTSVRIYLPRKAVVMETGQKKLPLLVYFHGGGFIMESAFSPVYHTFLTSTVSASGCIAVSVDYRRAPENPIPAAYEDSWEAVKWIFTHVAGSGPEAWINEKADFSRVVLAGDSAGANIAHHMLIRAGRENFEISGMALIHPYFLSKVEEEEEAEDAMRYMVGIWEIASLNRGVEDPWINVVGSDLSGLGCGRVLVMVAGNDVLAKEGRGYKVALEKCGWEREVEVVETEGECHLFHLKCPDSDNSRLVLNKFVEFLI
>Spe00363.t1
MAGDSAGANMCHHMAMRAGKENLEPRIKGIVMIHPAFWGKDPVDEFDEQDLDTRSGITEIWEKIASPNSVKGTDDPLFNVVGSESDLTGLGCDKVLVAMAGKDVFVRQGLAYAAKLEKSGWKGMVEVVVEDEEGHVFHLQNPNCKNALKFMKKVVEFIVG
>Spe03919.t1
MTSRLSFIFKKFCTHHYFVAGAKKKATFLVTESLIVGLIFSFFRISTKQLHQSRFLFPMESIKKQVSLELLPWLVVHSDGSLDRLVGTEVCPPGLDQETKVLSKDIIIEHKTGLSARIYRPDSVQPGQKLPLVLYFHGGAFLISSPAFPNYHNSLNKLVAMANIIAVSVDYRLAPEHPLPTAYEDSWNALQAILVVNEPWINDYADLDRFFLVGDSAGANISHHLAFRTKQSDSAVKIKGIGMIHPYFWGTEPIGFEVNDEARKKMVDGWWAFVCPSEKGSDDPWINPFADGSPELEGLGCERVMITVAEKDILSERGKMYYERLLKSKWRGKVEMLETKGKDHVFHIFEPDSDEAIEMLQRLAFFINQVQG
>Spe05039.t1
MDSEISFDNSPFYIVYKSGRIERLVGETIVPPSLTPQNGVVSKDVVFSPEKNLSVRLYLPEKADNKLPLLVYFHGGGFIIETAFSPTYHTFLTSAVAAANCLAISVDYRRAPEFPIPIPYEDSWDSLEWIFSHISGAGPEDWINKHADFSRVLVGGDSAGANIAHHLAIRARTEMKVIISGMILIHPYFWGKTPIDELETRDVSTREAIERKWGIASPNSENGADDPWINVVGSEYSDLSGLSCGRVLVMVAGEDKLARQGLGYAKKLDKSGWEGEVEVMETDHEGHVFHLRNPGSDNARDLVKKFAEFINKNPLVNHLYFFPLSSYYKKCWREMYMIESKAGAISCMLLALIFLGTWPALISLTERRGRLPQHTYLDYTLTNLLAAVIIALTLGEIGPSRPNFISQLSQENWQSVMFAMAGGIVLSLGNLATQYAWAFVGLSVTEVITASITVVIGTTLNYFLDDRINRAEVLFPGVACFLIAVCFASAVHKSNAADNKSKLQDFKSLELATTSTSQTETNPANGKAKEGTAAFLIELEKQRAIKVFGKSTVIGLAITFFAGICFSLFSPAFNLATNDQWHTLKHGVPKLDVYTAFFYFSISAFVVALILNISFLYWPVLGLPRSSFQAYLNDWNGRGWSFLAGFLCGFGNGLQFMGGQAAGYAAADAVQALPLVSTFWGILLFGEYRRSSRKTYILLISMLFMFIVAVAVLMASSGHRK
>Spe07262.t1
MATISFSHNHQSSDKRRGGSHHNRHGPVVEEIEGLIKVFNDGCVERPPIVPTVPPTLHPSSKVTSFDIKLSNDTSTRVYIPVSAVASPGVALPLILYFHGGGFCVGSAAWSCYHDFLTNLADKACCVVVSVNYRLAPEHRLPAAYDDGVNVLSWLVKQKISKRGYDSWVSKCNLSNVFLAGDSAGANIAYQVAFRIAASGRYVNTLNLKGIILIHPFFGGESRTPSEKQEFNNKSTALTLSASDTYWRLALPRGASRDHPWCNPRFNEAKLQLPETIVFVAEHDILKDRNMEMCKGMRSHVKKVESIIHGGVGHAFHILDNSSSVSRDRIHDMMCRLYNFINP
>Spe13120.t1
MESELVSEHPPFCRIFKDGHVERLTGTQIIPPSLDPTNDVVSKDVVYSPHHNLSVRLFLPHKSFAGDVNKLPLLIYIHGGAWIIESPFSPIYHTYLTDIVKSANCLAVSVQYRRAPEDPVPAAYEDSWSAIEWVFSHSVGDGPDDWINKHADFNRVFLAGDSAGANMSHHMAMRAGKEKLKPRIKGVAIVHPAFWGKDPVDEEDVQDVEIRKAIGGVWENMVSPNSVNGMDDPLFNAVGSGSDFSEMGCEKVLVAVAGKDVFVRQGLGYAAKLKKSGWKGDVEMVEEEEEGHVFHLQNPNSEKALKLLNKFVEFIVG
>Spe13118.t1
MLRRIACSSLFFRHSSLSYSPTAACISGRYLRRLPTLTALRCICSRSSSDLVYEHPPFVRVYKDGRVERLSGTEIIPPSQTPQNGVVSKDVVYSSEHNLSVRIFLPHKSAAGDVNKLPLLIYIHGGAWIIESPFSPIYHNFLTDIVKSANCLAVSIQYRRAPEDPVPAAYEDSWSAIKWVFSHSGGDGPEDWINKHADFNRVFLAGDSAGANMSHHMAMRAGKEKLKPRIKGVAIVHPAFWGKDPVDEHDVKDVEIRRRIGEVWENIASPNSVVGVDDPLFNVVGSGSDFSGFGSEKVLVAVAGKDVFVRQGLGYAEKLKKSGWEGDVMVVEEEDGDHCFHLLKPDSQNAPKLMKKFVEFITS
>Spe18562.t1
MNLSSHQQSYITLASNTKNIQMATISFSHNHHQSSSDNRRGHHRHGPVVEEIEGLIKVFNDGCVERQPIVPLVSPAVHPSTKLTSFDNRLSNETSTRVYIPDASLTLPLVVYFHGGGFCVGSAAWSCYHDFLTSLAVKARCVVVSVNYRLAPEHRLPAAYDDGVNVVSWLVNGGHSWLSKCNLSNVFLAGDSAGANVAYQVSLRAGTSGKPVNSLNFKGLILIHPFFGGESRTSSEKQQHHSKSTALTLSASDTYWRLALPRGASRDHPWCNPMASLKLPAATMVFMAEYDILKDRNMEMCKAMMMMRSHGKKVEGVVHGGVGHAFNILDNSLVSRERVHDMLCRVHNFIHP
>Spe19767.t1
MDSEIALDASPILKVYKSGRIERLIGENTVPPSLTPQNGVVSKDVVYDTHHNLSVRIYLPEKALETDDVSKLPLLVYYHGGGFIIETAFSPTYHTFLTAAVSASDCIAVSVDYRRAPEHPIPASYDDSWTALKWVFSHIEGTGPEPWLNKHADFKKVFMAGDSAGANIVHHMAMRAARETLSDSGISGIILVHPYFWSKTPVDEKETKDVSVRTKIEGIWMMASPNNREGTDDPWINVVQSESVDLSGLGCGKVLVMVAEKDALARQGWGYVAKLEKSGWKGKVELVESEGEDHVFHLTKPDCVKAIEAMKIFASFLKGDN
MDPDSEIAYDYPRYRVYKSGRIERLVTETFVPPSLNLENDVVSTDAVYSPEKNTSVRIYLPRKAVVMETGQKKLPLLVYFHGGGFIMESAFSPVYHTFLTSTVSASGCIAVSVDYRRAPENPIPAAYEDSWEAVKWIFTHVAGSGPEAWINEKADFSRVVLAGDSAGANIAHHMLIRAGRENFEISGMALIHPYFLSKVEEEEEAEDAMRYMVGIWEIASLNRGVEDPWINVVGSDLSGLGCGRVLVMVAGNDVLAKEGRGYKVALEKCGWEREVEVVETEGECHLFHLKCPDSDNSRLVLNKFVEFLI
>Spe00363.t1
MAGDSAGANMCHHMAMRAGKENLEPRIKGIVMIHPAFWGKDPVDEFDEQDLDTRSGITEIWEKIASPNSVKGTDDPLFNVVGSESDLTGLGCDKVLVAMAGKDVFVRQGLAYAAKLEKSGWKGMVEVVVEDEEGHVFHLQNPNCKNALKFMKKVVEFIVG
>Spe03919.t1
MTSRLSFIFKKFCTHHYFVAGAKKKATFLVTESLIVGLIFSFFRISTKQLHQSRFLFPMESIKKQVSLELLPWLVVHSDGSLDRLVGTEVCPPGLDQETKVLSKDIIIEHKTGLSARIYRPDSVQPGQKLPLVLYFHGGAFLISSPAFPNYHNSLNKLVAMANIIAVSVDYRLAPEHPLPTAYEDSWNALQAILVVNEPWINDYADLDRFFLVGDSAGANISHHLAFRTKQSDSAVKIKGIGMIHPYFWGTEPIGFEVNDEARKKMVDGWWAFVCPSEKGSDDPWINPFADGSPELEGLGCERVMITVAEKDILSERGKMYYERLLKSKWRGKVEMLETKGKDHVFHIFEPDSDEAIEMLQRLAFFINQVQG
>Spe05039.t1
MDSEISFDNSPFYIVYKSGRIERLVGETIVPPSLTPQNGVVSKDVVFSPEKNLSVRLYLPEKADNKLPLLVYFHGGGFIIETAFSPTYHTFLTSAVAAANCLAISVDYRRAPEFPIPIPYEDSWDSLEWIFSHISGAGPEDWINKHADFSRVLVGGDSAGANIAHHLAIRARTEMKVIISGMILIHPYFWGKTPIDELETRDVSTREAIERKWGIASPNSENGADDPWINVVGSEYSDLSGLSCGRVLVMVAGEDKLARQGLGYAKKLDKSGWEGEVEVMETDHEGHVFHLRNPGSDNARDLVKKFAEFINKNPLVNHLYFFPLSSYYKKCWREMYMIESKAGAISCMLLALIFLGTWPALISLTERRGRLPQHTYLDYTLTNLLAAVIIALTLGEIGPSRPNFISQLSQENWQSVMFAMAGGIVLSLGNLATQYAWAFVGLSVTEVITASITVVIGTTLNYFLDDRINRAEVLFPGVACFLIAVCFASAVHKSNAADNKSKLQDFKSLELATTSTSQTETNPANGKAKEGTAAFLIELEKQRAIKVFGKSTVIGLAITFFAGICFSLFSPAFNLATNDQWHTLKHGVPKLDVYTAFFYFSISAFVVALILNISFLYWPVLGLPRSSFQAYLNDWNGRGWSFLAGFLCGFGNGLQFMGGQAAGYAAADAVQALPLVSTFWGILLFGEYRRSSRKTYILLISMLFMFIVAVAVLMASSGHRK
>Spe07262.t1
MATISFSHNHQSSDKRRGGSHHNRHGPVVEEIEGLIKVFNDGCVERPPIVPTVPPTLHPSSKVTSFDIKLSNDTSTRVYIPVSAVASPGVALPLILYFHGGGFCVGSAAWSCYHDFLTNLADKACCVVVSVNYRLAPEHRLPAAYDDGVNVLSWLVKQKISKRGYDSWVSKCNLSNVFLAGDSAGANIAYQVAFRIAASGRYVNTLNLKGIILIHPFFGGESRTPSEKQEFNNKSTALTLSASDTYWRLALPRGASRDHPWCNPRFNEAKLQLPETIVFVAEHDILKDRNMEMCKGMRSHVKKVESIIHGGVGHAFHILDNSSSVSRDRIHDMMCRLYNFINP
>Spe13120.t1
MESELVSEHPPFCRIFKDGHVERLTGTQIIPPSLDPTNDVVSKDVVYSPHHNLSVRLFLPHKSFAGDVNKLPLLIYIHGGAWIIESPFSPIYHTYLTDIVKSANCLAVSVQYRRAPEDPVPAAYEDSWSAIEWVFSHSVGDGPDDWINKHADFNRVFLAGDSAGANMSHHMAMRAGKEKLKPRIKGVAIVHPAFWGKDPVDEEDVQDVEIRKAIGGVWENMVSPNSVNGMDDPLFNAVGSGSDFSEMGCEKVLVAVAGKDVFVRQGLGYAAKLKKSGWKGDVEMVEEEEEGHVFHLQNPNSEKALKLLNKFVEFIVG
>Spe13118.t1
MLRRIACSSLFFRHSSLSYSPTAACISGRYLRRLPTLTALRCICSRSSSDLVYEHPPFVRVYKDGRVERLSGTEIIPPSQTPQNGVVSKDVVYSSEHNLSVRIFLPHKSAAGDVNKLPLLIYIHGGAWIIESPFSPIYHNFLTDIVKSANCLAVSIQYRRAPEDPVPAAYEDSWSAIKWVFSHSGGDGPEDWINKHADFNRVFLAGDSAGANMSHHMAMRAGKEKLKPRIKGVAIVHPAFWGKDPVDEHDVKDVEIRRRIGEVWENIASPNSVVGVDDPLFNVVGSGSDFSGFGSEKVLVAVAGKDVFVRQGLGYAEKLKKSGWEGDVMVVEEEDGDHCFHLLKPDSQNAPKLMKKFVEFITS
>Spe18562.t1
MNLSSHQQSYITLASNTKNIQMATISFSHNHHQSSSDNRRGHHRHGPVVEEIEGLIKVFNDGCVERQPIVPLVSPAVHPSTKLTSFDNRLSNETSTRVYIPDASLTLPLVVYFHGGGFCVGSAAWSCYHDFLTSLAVKARCVVVSVNYRLAPEHRLPAAYDDGVNVVSWLVNGGHSWLSKCNLSNVFLAGDSAGANVAYQVSLRAGTSGKPVNSLNFKGLILIHPFFGGESRTSSEKQQHHSKSTALTLSASDTYWRLALPRGASRDHPWCNPMASLKLPAATMVFMAEYDILKDRNMEMCKAMMMMRSHGKKVEGVVHGGVGHAFNILDNSLVSRERVHDMLCRVHNFIHP
>Spe19767.t1
MDSEIALDASPILKVYKSGRIERLIGENTVPPSLTPQNGVVSKDVVYDTHHNLSVRIYLPEKALETDDVSKLPLLVYYHGGGFIIETAFSPTYHTFLTAAVSASDCIAVSVDYRRAPEHPIPASYDDSWTALKWVFSHIEGTGPEPWLNKHADFKKVFMAGDSAGANIVHHMAMRAARETLSDSGISGIILVHPYFWSKTPVDEKETKDVSVRTKIEGIWMMASPNNREGTDDPWINVVQSESVDLSGLGCGKVLVMVAEKDALARQGWGYVAKLEKSGWKGKVELVESEGEDHVFHLTKPDCVKAIEAMKIFASFLKGDN
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University