Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Striga asiatica
Species name
Witchweed (Striga asiatica) is a species of eudicot in the family Orobanchaceae.
Species info
Gene sequence info
Striga_asiatica.4CL.fa
Download
>SGA_v2.0_scaffold5T02825
MEPTTKSKDIIFRSKLPDIYIPKHLPLHTYCFENISRFGSRPCLINGSTGEILTYDQVELASRRVGSGLHRLGIRQGDTIMLLLPNSPEFVLAFLGASHIGAVSTMANPFFTPAEVVKQAAASRAKLIVTQACHVDKVRDYAAEHGVKVVCVDGAPPEECLPFSEVASGDEAELPAVKISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHSDDVIMCVLPLFHIYSLNSIMLCGLRVGAAILIMQKFEIVPFLELIQRYRVTIGPFVPPIVLAIEKSPVVEKYDLSSVRTVMSGAAPLGRELEDAVRLKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDTETGASLGRNQPGEICIRGDQIMKGYLNDPESTERTIDKEGWLHTGDIGFIDDDDELFIVDRLKEIIKYKGFQVAPAELEALLLNHPNISDAAVVSMKDEQAGEVPVAYVVKSNGSTITEDEIKQFVSKQVIFYKRINRVFFIDAIPKSPSGKILRKDLRARLAAGVPN
>SGA_v2.0_scaffold50T18443
MLSVASVETAQNSSEPPSPPLSSLPREHVFVSKLPPIPIPTDVPLHTYCFQNASLYPDRTCLLVGSTGQSYTFAQTHLISRKVAAGLSTLCGIRKGDVLMLLLQNSPEFVFTFMAASILGAAVTTANPFCTSKEIFKQFHLSRAKLIVTHSQYVDKLRHSDGVFGEDFKVVTVDDGPAPDGCLHFSELSKANEKDVAADVEIKPKEDAVALPFSSGTTGLPKGVVLTHGSLIASVAQQVDGENPNLHLRPDDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLLMHKFEIGSLLELIQRHRVSVAAVVPPLVLALAKNSMVDSFDLSSIRMVLSGAAPLGKELEAALLTRLPQAVLGQGYGMTEAGPVLSMSPSFAKHPLPTKSGSCGNVVRNAELKVVDPETGCSLPRNQPGEICIRYLNDDEATARTIDVEGWLHTGDIGYVDDDDDWIESRSLSNSKAFSQKDEAAGEVPVAFVVPAKGSHLTEEAIKEFISKQVVFYKRLHKVYFVHAIPKSPAGKILRKELRAKLAALPSST
>SGA_v2.0_scaffold66T22461
MESQTERETIFRSKLPTIHIPTHLPTHEYLFENLPRHATRPALIDAATGSTLTHADVRLAARRAAAAFLRLGVRSGHVVMLLLHNSPDFAVSFLAASFAGATAAAANPRFTAAELSSQANLSKPKLIVTHVPYLEKANRLARELGADVAVVEFSDLTKSDGESVSDVEVRSSDMAALLFSSGTTGLPKGVMLTHRNLITSTAQLADGENPSCCVGSGDVVLCVLPMFHVLGLSMLLLGLRAGATVLVVPKFEIGVMLELIQKYRVTIVPLVPPVLLAVAKRPEEELFDLSSVRIVLSGGAPLDEKLQAAVGAKFPNATVGQGYGMTETGVISLCPGFAKNPSDYKPGSCGAIIRNMELKIVDPLTGASLSRSHVGEICVRGNSVMKGYYNDAEATKRTIDGEGWLHTGDLGYVDGDSELFIVDRLKELIKYKGFHVAPAEIEALLIHHPSISDAAVLPKKDERAGEVPVAFVVPTIGSNITEHEIKQYISNQVVPYKRIHRVFFIDEIPKAPSGKILRKNLRARI
>SGA_v2.0_scaffold69T23269
KKHSKNPKYSSSNSVRSMESRAYANDHIFRSKLPAIPIPDHLPVHAYIFQNLHRHPSSTALIDSATGKTLTHSEVELAARKLAAGLHARLGIRRGHVIMLLLHNSPEFVISFLAASMAGATVTTANPNYTASEIASQAAVSGPAVVITHSCYAGKVTSSSGARNTKVLTIDSRRFSELAESDERLLPESGGGGFRPSDTAVLLFSSGTTGMPKAVMLSHRNLVACLEQQGGGENPNFHVDGETDVALCVLPLFHMYSLTMVLAEFGAVLEAIGRYQVTIAPLVPPALLEIVNSSGAGGGKYDLSTVRKVYSGAAPMGRELEAAVRANFPNAVIGQGYGMTEGGVISICLGFAKKPFGFKSGSCGTVVRNVEMKVVDPLTGASLSRNQKGEICVRGASIMKGYYNDPEATKRTIDGEGWLHTGDIGYVDDDDELFIVDRLKELIKYKGFHVAPAELEALLIAHPSISDAAVVPMKDEAAGEVPVAFVVPANSSNISEEDIKQYISKLVVSYKRINKVFFTKKIPRAPSGKILRKNLRSRI
>SGA_v2.0_scaffold69T23265
MESKAYENDNHIFRSKLPDIPIPDHLPVHAYIFQNLHRHPSRPALIDSATGKTLTHSEVELAAGKLAAGLHGRLGIRRGHVIMLLLHNSPEFVISFLAASMAGATVTTANPNYTASEIASQAAVSGPAVVITHSSYAGKVTSSSGARNPIVLTIDSRRFSELEESDERLLPESGGGRSSDTAALLFSSGTTGMPKAVMLSHRNLVACLAQKGGGENPNFHVDGERDVALCVLPLFHVFSLAMVLVVIRAGAAVVIMPRFEVGAVLEAIGRYRVTIAPLVPPALLAIVKSSAAGGGKYDLSTVRKVYSGAAPMGRELEAAVRERLPNAVIGQGYGMTEAGVISISLGFAKKPFGFKSGSCGTVVRNVEMKVIDPLTGASLSRNQKGEICVRGVSIMKGYYNDLEATKRTIDGDGWLHTGDIGYVDDDDELFIVDRLKELIKYKGFHVAPAELEALLIAHPSISDAAVAPAELEALLIAHPSISDAAVVPMKDEAAGEVPVAFVVPTNGSNISEEDIKQKKKHIVVSYKQINRVFFTKEIPRAPSGKILRKNLRSRI
>SGA_v2.0_scaffold148T36474
MGIDEEIIFRSKYGDVEVPSHLTLPEFVLENVESYYENVAFVDAITGKGYTYRQVKSDVHRFSKALRSLGLRKGQVVVVLLPNVAEYATVALGIMAAGGVFSGANPNAHISEIQKQVEAADAKLIVTDGSTYHKAKDLSLPVIIQGEDRVEGTIYWDELLVAAEKAGTAVNDEKVQQTDLCALPFSSGTTGLSKGVMLTHRNLVANLCSSLFSVGPELIGQVTILGLIPFFHIYGLTGICCASIRNKGKVVVMQRYELRLFMNALIGHQVTFAPIVPPIILALVKNPIVDEFDLTKLNLKSIMTAAAPLAPEILYEFEKKFPGVEVQEAYGMTEHSCITLSHADPSKGHSVAKKNSVGFILPNLEVKFVDPDTGVSLPNNTPGEICVRSQCVMKGYYKNEHETNLTIDKDGWLHTGDIGYIDEDGDVFLVDRIKELIKYKGFQVAPAELEAILLTHPSVEDAAVVGLPDEEAGEIPAACVVINKNAKESEQDMINYVSSNVASYKRVRLLQFVDTIPKSPSGKIMRRLIKETMLNSKPATELNSV
>SGA_v2.0_scaffold180T39600
MEKSGYGRDGVYRSLAPPIFAPTDPNLSMISFLFRNASSFPDKRALIDSHTGETLTFAHLKSTVSRVAHSLLHLGITKNDVVLIFAPNSIQFPLSFFAIAALGAITTTANPTYTTSELSKQVIDSTAKLIITVEDLLPKVKDFGLPVVLLNSHVKPISPNIGKNKIPSITDLLNNGGGSLDLDNNFNNIKQDDTAALLYSSGTTGTSKGVILTHRNFISSALMVTTYQEFAGESDNVFLCFLPMFHVFGLAAILYAQLQRGNAVVSMSRFDLELILKMVEKYGVTHLWVVPPIVLGLAKSPIVKKYDLSSLKQIGSGAAPLGRELMQECAKNFPRAVVVQGYGMTETCGIASLENPYIGPRHTGSAGILAPGVEAQIVSVDKLKPLPPGQLGEIWLRGPNTMKGYFNNPKATKHTIDKQGWVHTGDLGYFDEEGQLYVVDRIKELIKYKGFQVAPAELEGLLVFPDAEAGEVPIAYVVRAPNSLLTEEDIKKFIADQVAPYKRLKKVTFVNMVPKSAAGKILRKDLIDKVRSKL
>SGA_v2.0_scaffold263T45968
MEKSGYGRDGVYRSLRPPLFAPKDPNLSMVSFLFRNASSFPHKRALIDSHTGETLTFAQLKSAVSKVAHGLLQLGISKNDVVLIFSPNSIQFPICFLGIVAVGAIATTVNPMYTVSELSKQVHDSTARLIITVEDLLLKVKDFSLPVVLLNSASKSSSPVGKIPSITLFTELVNNGGSVNLDSNFGKIKQDDAAALLYSSGTTGTSKGVILTHGNFISGALMVTSDQESAGESDNVFLCFLPMFHVFGLAVILYSQLQRGNAVISMSRFDLELILKMVEKYRVTHMWVVPPIVLGLAKSPVVKNYDLSSLKQIGSGAAPLGRELMQECAKNFPRAVVNQGYGMTETCGIVSIENPYAGPRHTGSAGLLVPGVESQIVSVDKLKPLPPGQLGEIWVRGPNMMKGYFNNPKATMQTIDKQGWVHTGDLGYFDEEGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEISDAVVIPFPDAEAGEVPIAYVVKAPNSSLTEEDIKKFIADQDPLIYIAFRTAIENKEESRCSGEPPITTNHNKVNQLPFSLCLSNFDFTSLRSFPQLRESLTSWIRLPLRQRWGNGEGSRIPILVMGDCPSRRKRKDAKAPECSDPGSNPAELISLEPTTVGVV
MEPTTKSKDIIFRSKLPDIYIPKHLPLHTYCFENISRFGSRPCLINGSTGEILTYDQVELASRRVGSGLHRLGIRQGDTIMLLLPNSPEFVLAFLGASHIGAVSTMANPFFTPAEVVKQAAASRAKLIVTQACHVDKVRDYAAEHGVKVVCVDGAPPEECLPFSEVASGDEAELPAVKISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHSDDVIMCVLPLFHIYSLNSIMLCGLRVGAAILIMQKFEIVPFLELIQRYRVTIGPFVPPIVLAIEKSPVVEKYDLSSVRTVMSGAAPLGRELEDAVRLKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDTETGASLGRNQPGEICIRGDQIMKGYLNDPESTERTIDKEGWLHTGDIGFIDDDDELFIVDRLKEIIKYKGFQVAPAELEALLLNHPNISDAAVVSMKDEQAGEVPVAYVVKSNGSTITEDEIKQFVSKQVIFYKRINRVFFIDAIPKSPSGKILRKDLRARLAAGVPN
>SGA_v2.0_scaffold50T18443
MLSVASVETAQNSSEPPSPPLSSLPREHVFVSKLPPIPIPTDVPLHTYCFQNASLYPDRTCLLVGSTGQSYTFAQTHLISRKVAAGLSTLCGIRKGDVLMLLLQNSPEFVFTFMAASILGAAVTTANPFCTSKEIFKQFHLSRAKLIVTHSQYVDKLRHSDGVFGEDFKVVTVDDGPAPDGCLHFSELSKANEKDVAADVEIKPKEDAVALPFSSGTTGLPKGVVLTHGSLIASVAQQVDGENPNLHLRPDDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLLMHKFEIGSLLELIQRHRVSVAAVVPPLVLALAKNSMVDSFDLSSIRMVLSGAAPLGKELEAALLTRLPQAVLGQGYGMTEAGPVLSMSPSFAKHPLPTKSGSCGNVVRNAELKVVDPETGCSLPRNQPGEICIRYLNDDEATARTIDVEGWLHTGDIGYVDDDDDWIESRSLSNSKAFSQKDEAAGEVPVAFVVPAKGSHLTEEAIKEFISKQVVFYKRLHKVYFVHAIPKSPAGKILRKELRAKLAALPSST
>SGA_v2.0_scaffold66T22461
MESQTERETIFRSKLPTIHIPTHLPTHEYLFENLPRHATRPALIDAATGSTLTHADVRLAARRAAAAFLRLGVRSGHVVMLLLHNSPDFAVSFLAASFAGATAAAANPRFTAAELSSQANLSKPKLIVTHVPYLEKANRLARELGADVAVVEFSDLTKSDGESVSDVEVRSSDMAALLFSSGTTGLPKGVMLTHRNLITSTAQLADGENPSCCVGSGDVVLCVLPMFHVLGLSMLLLGLRAGATVLVVPKFEIGVMLELIQKYRVTIVPLVPPVLLAVAKRPEEELFDLSSVRIVLSGGAPLDEKLQAAVGAKFPNATVGQGYGMTETGVISLCPGFAKNPSDYKPGSCGAIIRNMELKIVDPLTGASLSRSHVGEICVRGNSVMKGYYNDAEATKRTIDGEGWLHTGDLGYVDGDSELFIVDRLKELIKYKGFHVAPAEIEALLIHHPSISDAAVLPKKDERAGEVPVAFVVPTIGSNITEHEIKQYISNQVVPYKRIHRVFFIDEIPKAPSGKILRKNLRARI
>SGA_v2.0_scaffold69T23269
KKHSKNPKYSSSNSVRSMESRAYANDHIFRSKLPAIPIPDHLPVHAYIFQNLHRHPSSTALIDSATGKTLTHSEVELAARKLAAGLHARLGIRRGHVIMLLLHNSPEFVISFLAASMAGATVTTANPNYTASEIASQAAVSGPAVVITHSCYAGKVTSSSGARNTKVLTIDSRRFSELAESDERLLPESGGGGFRPSDTAVLLFSSGTTGMPKAVMLSHRNLVACLEQQGGGENPNFHVDGETDVALCVLPLFHMYSLTMVLAEFGAVLEAIGRYQVTIAPLVPPALLEIVNSSGAGGGKYDLSTVRKVYSGAAPMGRELEAAVRANFPNAVIGQGYGMTEGGVISICLGFAKKPFGFKSGSCGTVVRNVEMKVVDPLTGASLSRNQKGEICVRGASIMKGYYNDPEATKRTIDGEGWLHTGDIGYVDDDDELFIVDRLKELIKYKGFHVAPAELEALLIAHPSISDAAVVPMKDEAAGEVPVAFVVPANSSNISEEDIKQYISKLVVSYKRINKVFFTKKIPRAPSGKILRKNLRSRI
>SGA_v2.0_scaffold69T23265
MESKAYENDNHIFRSKLPDIPIPDHLPVHAYIFQNLHRHPSRPALIDSATGKTLTHSEVELAAGKLAAGLHGRLGIRRGHVIMLLLHNSPEFVISFLAASMAGATVTTANPNYTASEIASQAAVSGPAVVITHSSYAGKVTSSSGARNPIVLTIDSRRFSELEESDERLLPESGGGRSSDTAALLFSSGTTGMPKAVMLSHRNLVACLAQKGGGENPNFHVDGERDVALCVLPLFHVFSLAMVLVVIRAGAAVVIMPRFEVGAVLEAIGRYRVTIAPLVPPALLAIVKSSAAGGGKYDLSTVRKVYSGAAPMGRELEAAVRERLPNAVIGQGYGMTEAGVISISLGFAKKPFGFKSGSCGTVVRNVEMKVIDPLTGASLSRNQKGEICVRGVSIMKGYYNDLEATKRTIDGDGWLHTGDIGYVDDDDELFIVDRLKELIKYKGFHVAPAELEALLIAHPSISDAAVAPAELEALLIAHPSISDAAVVPMKDEAAGEVPVAFVVPTNGSNISEEDIKQKKKHIVVSYKQINRVFFTKEIPRAPSGKILRKNLRSRI
>SGA_v2.0_scaffold148T36474
MGIDEEIIFRSKYGDVEVPSHLTLPEFVLENVESYYENVAFVDAITGKGYTYRQVKSDVHRFSKALRSLGLRKGQVVVVLLPNVAEYATVALGIMAAGGVFSGANPNAHISEIQKQVEAADAKLIVTDGSTYHKAKDLSLPVIIQGEDRVEGTIYWDELLVAAEKAGTAVNDEKVQQTDLCALPFSSGTTGLSKGVMLTHRNLVANLCSSLFSVGPELIGQVTILGLIPFFHIYGLTGICCASIRNKGKVVVMQRYELRLFMNALIGHQVTFAPIVPPIILALVKNPIVDEFDLTKLNLKSIMTAAAPLAPEILYEFEKKFPGVEVQEAYGMTEHSCITLSHADPSKGHSVAKKNSVGFILPNLEVKFVDPDTGVSLPNNTPGEICVRSQCVMKGYYKNEHETNLTIDKDGWLHTGDIGYIDEDGDVFLVDRIKELIKYKGFQVAPAELEAILLTHPSVEDAAVVGLPDEEAGEIPAACVVINKNAKESEQDMINYVSSNVASYKRVRLLQFVDTIPKSPSGKIMRRLIKETMLNSKPATELNSV
>SGA_v2.0_scaffold180T39600
MEKSGYGRDGVYRSLAPPIFAPTDPNLSMISFLFRNASSFPDKRALIDSHTGETLTFAHLKSTVSRVAHSLLHLGITKNDVVLIFAPNSIQFPLSFFAIAALGAITTTANPTYTTSELSKQVIDSTAKLIITVEDLLPKVKDFGLPVVLLNSHVKPISPNIGKNKIPSITDLLNNGGGSLDLDNNFNNIKQDDTAALLYSSGTTGTSKGVILTHRNFISSALMVTTYQEFAGESDNVFLCFLPMFHVFGLAAILYAQLQRGNAVVSMSRFDLELILKMVEKYGVTHLWVVPPIVLGLAKSPIVKKYDLSSLKQIGSGAAPLGRELMQECAKNFPRAVVVQGYGMTETCGIASLENPYIGPRHTGSAGILAPGVEAQIVSVDKLKPLPPGQLGEIWLRGPNTMKGYFNNPKATKHTIDKQGWVHTGDLGYFDEEGQLYVVDRIKELIKYKGFQVAPAELEGLLVFPDAEAGEVPIAYVVRAPNSLLTEEDIKKFIADQVAPYKRLKKVTFVNMVPKSAAGKILRKDLIDKVRSKL
>SGA_v2.0_scaffold263T45968
MEKSGYGRDGVYRSLRPPLFAPKDPNLSMVSFLFRNASSFPHKRALIDSHTGETLTFAQLKSAVSKVAHGLLQLGISKNDVVLIFSPNSIQFPICFLGIVAVGAIATTVNPMYTVSELSKQVHDSTARLIITVEDLLLKVKDFSLPVVLLNSASKSSSPVGKIPSITLFTELVNNGGSVNLDSNFGKIKQDDAAALLYSSGTTGTSKGVILTHGNFISGALMVTSDQESAGESDNVFLCFLPMFHVFGLAVILYSQLQRGNAVISMSRFDLELILKMVEKYRVTHMWVVPPIVLGLAKSPVVKNYDLSSLKQIGSGAAPLGRELMQECAKNFPRAVVNQGYGMTETCGIVSIENPYAGPRHTGSAGLLVPGVESQIVSVDKLKPLPPGQLGEIWVRGPNMMKGYFNNPKATMQTIDKQGWVHTGDLGYFDEEGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEISDAVVIPFPDAEAGEVPIAYVVKAPNSSLTEEDIKKFIADQDPLIYIAFRTAIENKEESRCSGEPPITTNHNKVNQLPFSLCLSNFDFTSLRSFPQLRESLTSWIRLPLRQRWGNGEGSRIPILVMGDCPSRRKRKDAKAPECSDPGSNPAELISLEPTTVGVV
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University