Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Sonneratia alba
Species name
Sonneratia alba is a species of eudicot in the family Lythraceae (loosestrife family).
Species info
Gene sequence info
Sonneratia_alba.4CL.fa
Download
>evm.model.scaffold_330.40
MEPKQETLGQEFIFRSKLPDIYIPNHLPLHSYCFENISEFQDRPCIIDGSSGKIYTYSEVELTARRAASGLNKIGIEQGHVIMLLLQNSPEFMLAFLGASYRGAMSTTANPFCTPAEIAKQAAASKAKLIITQAEFAPKVKQYAEENGVKVMCIDSAPEGCLHFSELTQADEAEMPAVKIDPNDAVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFCKEDVIMCVLPLFHIYSLNSIMLCGLRVGAAILIMQKFEIVKLLELVQKCKVTIAPFVPPIVLAIAKNADVDKYDLSSIRTVMSGAAPMGKELEDTVRAKLPNARLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPDTGASLPRNQPGEICIRGSQIMKGYLNDPEATERTIDKEGWLHTGDIGFIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLIAHPSISDAAVVPMKDEAAGEVPVAFVVRSNGSKISEDEIKQYISKQVVFYKRINKVFFTEAIPKAPSGKILRKDLRAKLASGVYA
>evm.model.scaffold_407.5
MISVAPSLESQPSADSIAPTCHNAPAAAGGRGDDIIFRSRLPDITVPNHLPLHTYCFQSLPESADRPCLIVGSTGKSFTYAETHLICRKVAAGLSNLGISHGDVIMILLPNCPEFVFTFMGASMIGAVSTTANPFYTPTEILKQFKASGAKLIVTQSHYVEKLRDFNKDSEGGGGMGEDFTVITVDDTPENCLHFSVLSEANESQLLLREQEEEAYTTTRFDPDDPVALPFSSGTTGLPKGVMLTHRSLITSVAQQVDGENPNLHLMDSDVVLCVLPLFHIFSLNSVLLCSLRAGSTVLLMHKFEIGALLELIQRHRVSVAAVVPPLVLALAKNPMVEGHDLSSLRVILSGAAPLGKELEDALRSRVPQAVLGQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVRNAELKVIDPATGSSLGRNQPGEICIRGQQIMKGYLNDPEATARTIDVERWLHTGDIGFVDDDDEVFIVDRVKEIIKFKGFQVPPAELEALLVSHPSIADAAVVPQKDEAAGEVPVAFVVRSKGVEVSEEAAKEFIAKQVVFYKRLHKVYFIHAIPRSPSGKILRKDLKSKIAAAAASAASMPNPI
>evm.model.scaffold_1050.67
MAATHVNSTTEFPAWYSPETGIYDSTYPSIPLPESPFLDAVSYIFSHTHDGLSAFVDSSTGFSISYSELLRLVSCMACGLRQLGVSRGDVVLLLLPNSVYYPVAFLGVLYLGGVVTTMNPLSSLSEIRRQVADCGVRLAFACSDRLEEVRRLGVKVVAVPENGNGDWYKVEFMEFYGLISKSGGVDLDSAAKPVITQDDKAAIVYSSGTTGLSKGVVLTHRNLIAMVELFVKFEASQYNFLSSENVYLASLPMFHIYGLSLFVLGLLALGSKVVVMRRFNPREAVRTIDKYQVSHFPVVPPMLKALTKAAKSARETSSLKSLKQVSCGAASLNRRSIEEFVQTLPHLDFIQGYGMTESTAVGTRGFNSERFQKYSSIGLLAPNMQAKVVDWRTGYLNNAEATSLMIDEDGWLHTGDIIHFDNDGFLHILDRLKEIIKYKGFQIAPADLEAVLITHPEITDVAVAGAVDDECGEIPVAFVVRRNGSRISEDGLIDFVAKQVAPYKKVRKVVFTRSIPKSPAGKILRRELKRLFASRL
>evm.model.scaffold_922.385
MEERPLSGANGTLVPGVESKIISVKMVEPLLLNHTGESWLRGPSIVRGNTGLGDRAIPVFTMQNRGYYLNNLEATKITIDEQGRLHMRDLGYFKMRHNYLSSVDRLKHLIECYGFQVAPFKRLQTVNFIKQSSLPQVNIREDGEKRAQGEGSVQGVEQPKLVGPNMIHCICSGPITDASTDLT
>evm.model.scaffold_1290.32
MGTSAEFSAQDHEHIFRSRFPPVPVPDVSLPDFVLQGWEPHADKVAFVEAVSGKTYTHAEVVRDVQRFSKALRTIGLRKGQVVIVALPNVAEYGIVALGIMAARGVFSGANPTVHASEIKKQVDAADAKLIITDGPNYEKVRNFGLPVIVLDEGEPIPTAMNWRDLLQAGDRAGPGAAVEEEPAFQQDDLCALPFSSGTTGLSKGVMLTHRNLVANLCSTLFSVTPEMIGQVTTLGLIPFFHIYGTTGICCATIRNKGKVVVMNRYDLRTFLSALITHEVTFAPIVPPIILNLVKNPIVEEFDLSKLKLMAVMTAAAPLAPEILSAFETKFPGVLVQEAYGLTEHSCITLSHVGPAHGTAKKNSVGRILPNLEIKFIDPDTGLSLPQNTPGELCVRSQCVMQGYYNNKEETSRTIDKDGWLHTGDIGYIDDDGDVFIVDRIKELIKYKGFQVAPAELEAILLGHPSVEDAAVVPLPDEEAGEIPAACVVLSKGAKETEDDIMKFVASNIATYKKVRVVQFVESIPKSPSGKILRRLLRDRLLEKIEKP
>evm.model.scaffold_1290.170
MEPKKEAALSQEFIFRSKLPDIYVPNHLPLHSYCFENISEFQDRPCVIDGATGKIYTYSEVELTARRVASGLHKIGIEQGHVVMLLLQNSPEFVLAFLGASYRGAMSTTANPFCTPAEIAKQATASKAKLIITRAEFAPKVKNFSEENGIYTYIYIYRHNIILTACPSRVKVMCIDTAQEGCLHFSELTQADEAEIPVVKIDPNDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFRKEDVILCVLPLFHIYSLNSVMLCGLRVGAAILIMQKFDIVRFMELVQRYKVTIAPFVPPIVLAIAKNTEVDKYDLSSIRTVMSGAAPMGKELEDSVRAKLPNAKLGQGYGMTEAGPLLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPDTGASLPRNQAGEICIRGNQIMKGYLNDPEATERTIDKQGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLISHPDISDAAVVPMKDEAAGEVPVAFIVRSNGSKITEDEIKQYISKQVVFYKRIKRVFFIEAIPKAPSGKILRKDLRARLASGVYA
>evm.model.scaffold_983.330
MEKSGYGRDGIFRSLRPPLVLPKEPNLSMVSFLFKNSISFPDKPALIDADTDETLTFSQFKSAVVKVSHGLLHLGIKKNDVVLILAPNSIQFPVCFLGITAIGAIATTSNPLYTAAELSKQAKDSRPKMLITIPELWDKVKDFNLPSVFLGSKDFSHIKSTSRVLGFQDLINLSPTSSDFPAVSVRQTDTAVLLYSSGTTGTSKGVILTHRNFIATSLMINMDQELAGEMHNVFLCVLPMFHVFGLAVISFSRLTAGNLVVSIGKFEFESFLRAVEKYRVTDLWIVPPIVLALAKQSAVKKYDLSSLRCIGSGAAPLGKDVMEECAKNFPHAAVVQGYGMTETCAIVSVENPRVGIRHTGSAGMLASGVEAQIISVDTRKPLPPNQLGEIRVRGPNMMQGYYNNPEATKLTIDSKGWVHTGDLGYFDEEGRLFVVDRIKELIKYKGFQIAPAELEGLLLSHPKILDAVVIPFPDAEAGEVPIAYVVRSPNGSLTEEDVQKFIANQVAPFKRLRKVTFIQTIPKSASGKILRRELIEKVRSRM
>evm.model.scaffold_918.129
MERSGYGRDGIFRSLRPPLVLPREPNLSMVSFLFKNSISYPDRPALIDADSGETLTFSQCKSAVAKVSHGLIHLGIKKNDVVLIFAPNSIQYPVCFLGIAAIGAIATTSNPLYTAAELSKQVKNSRPKMVITVPELWDKVKDFNIPSIFLGTADFSHIKSRSRILGFQDFMNLSPASSDFPVVSVRQTDTAALLYSSGTTGTSKGVILTHRNFIAASLMINMDQELAGEVHNVFLCVLPMFHVFGLAVISYSQLRSGNTIVSMAKFEFESALRAVEKYRVTSLWIVPPIVLALSKQQGIVKKYDLSSLRHIGSGAAPLGKDVMEDCAKSIPQAAVSQGYGMTETCGIVSVENHRVATRHTGSTGMLASGVEAQIISVGTLKPLPPKQLGEIWVRGPNMMRGYYNNPQATKLTIDREGWVHTGDLGCFDEEGQLFVVDRIKELIKYKGYQIAPAELEGLLLSHPEILDAVVIPFPDAEAGEVPIAYVVRSPSSSLTEEDVQKFIADQVAPFKRLRRVTFTQTVPKSASGKILRRELIERTAKVFREIKQRLNSFPSLRQVRRNSSASWSFPTNNNEPPPKHGTFFHPHNFLLSALTNSPLKTSRRLTMAEDKDGGEKKSGGGEEGNKEVTKSGSKAVVLKVDFHCEGCASKIIKCAKAFEGAEKVRVEWEASKLTVEGKVDPAKLRERLQEKTKKKVELVSPQLSKDKKDKKDDNTTNSSDSNKGQGNKADEKKPKELPVTTVVLKLGLHCHGCVQKIHKFVSKTSGVNSVTIERQKDLVMVTGTMDVKALVKALKGRMNREVEVIPPKQEKEKGNSNEEKKKEGSANGNGGGKMKSGGGRGGGNCGNAGGNTEEPDCVGRVDGSRMEYFGTLGHLANTGYGCSFRHGQWYTYGETVHAPQYFSDENPNACSVM
MEPKQETLGQEFIFRSKLPDIYIPNHLPLHSYCFENISEFQDRPCIIDGSSGKIYTYSEVELTARRAASGLNKIGIEQGHVIMLLLQNSPEFMLAFLGASYRGAMSTTANPFCTPAEIAKQAAASKAKLIITQAEFAPKVKQYAEENGVKVMCIDSAPEGCLHFSELTQADEAEMPAVKIDPNDAVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFCKEDVIMCVLPLFHIYSLNSIMLCGLRVGAAILIMQKFEIVKLLELVQKCKVTIAPFVPPIVLAIAKNADVDKYDLSSIRTVMSGAAPMGKELEDTVRAKLPNARLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPDTGASLPRNQPGEICIRGSQIMKGYLNDPEATERTIDKEGWLHTGDIGFIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLIAHPSISDAAVVPMKDEAAGEVPVAFVVRSNGSKISEDEIKQYISKQVVFYKRINKVFFTEAIPKAPSGKILRKDLRAKLASGVYA
>evm.model.scaffold_407.5
MISVAPSLESQPSADSIAPTCHNAPAAAGGRGDDIIFRSRLPDITVPNHLPLHTYCFQSLPESADRPCLIVGSTGKSFTYAETHLICRKVAAGLSNLGISHGDVIMILLPNCPEFVFTFMGASMIGAVSTTANPFYTPTEILKQFKASGAKLIVTQSHYVEKLRDFNKDSEGGGGMGEDFTVITVDDTPENCLHFSVLSEANESQLLLREQEEEAYTTTRFDPDDPVALPFSSGTTGLPKGVMLTHRSLITSVAQQVDGENPNLHLMDSDVVLCVLPLFHIFSLNSVLLCSLRAGSTVLLMHKFEIGALLELIQRHRVSVAAVVPPLVLALAKNPMVEGHDLSSLRVILSGAAPLGKELEDALRSRVPQAVLGQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVRNAELKVIDPATGSSLGRNQPGEICIRGQQIMKGYLNDPEATARTIDVERWLHTGDIGFVDDDDEVFIVDRVKEIIKFKGFQVPPAELEALLVSHPSIADAAVVPQKDEAAGEVPVAFVVRSKGVEVSEEAAKEFIAKQVVFYKRLHKVYFIHAIPRSPSGKILRKDLKSKIAAAAASAASMPNPI
>evm.model.scaffold_1050.67
MAATHVNSTTEFPAWYSPETGIYDSTYPSIPLPESPFLDAVSYIFSHTHDGLSAFVDSSTGFSISYSELLRLVSCMACGLRQLGVSRGDVVLLLLPNSVYYPVAFLGVLYLGGVVTTMNPLSSLSEIRRQVADCGVRLAFACSDRLEEVRRLGVKVVAVPENGNGDWYKVEFMEFYGLISKSGGVDLDSAAKPVITQDDKAAIVYSSGTTGLSKGVVLTHRNLIAMVELFVKFEASQYNFLSSENVYLASLPMFHIYGLSLFVLGLLALGSKVVVMRRFNPREAVRTIDKYQVSHFPVVPPMLKALTKAAKSARETSSLKSLKQVSCGAASLNRRSIEEFVQTLPHLDFIQGYGMTESTAVGTRGFNSERFQKYSSIGLLAPNMQAKVVDWRTGYLNNAEATSLMIDEDGWLHTGDIIHFDNDGFLHILDRLKEIIKYKGFQIAPADLEAVLITHPEITDVAVAGAVDDECGEIPVAFVVRRNGSRISEDGLIDFVAKQVAPYKKVRKVVFTRSIPKSPAGKILRRELKRLFASRL
>evm.model.scaffold_922.385
MEERPLSGANGTLVPGVESKIISVKMVEPLLLNHTGESWLRGPSIVRGNTGLGDRAIPVFTMQNRGYYLNNLEATKITIDEQGRLHMRDLGYFKMRHNYLSSVDRLKHLIECYGFQVAPFKRLQTVNFIKQSSLPQVNIREDGEKRAQGEGSVQGVEQPKLVGPNMIHCICSGPITDASTDLT
>evm.model.scaffold_1290.32
MGTSAEFSAQDHEHIFRSRFPPVPVPDVSLPDFVLQGWEPHADKVAFVEAVSGKTYTHAEVVRDVQRFSKALRTIGLRKGQVVIVALPNVAEYGIVALGIMAARGVFSGANPTVHASEIKKQVDAADAKLIITDGPNYEKVRNFGLPVIVLDEGEPIPTAMNWRDLLQAGDRAGPGAAVEEEPAFQQDDLCALPFSSGTTGLSKGVMLTHRNLVANLCSTLFSVTPEMIGQVTTLGLIPFFHIYGTTGICCATIRNKGKVVVMNRYDLRTFLSALITHEVTFAPIVPPIILNLVKNPIVEEFDLSKLKLMAVMTAAAPLAPEILSAFETKFPGVLVQEAYGLTEHSCITLSHVGPAHGTAKKNSVGRILPNLEIKFIDPDTGLSLPQNTPGELCVRSQCVMQGYYNNKEETSRTIDKDGWLHTGDIGYIDDDGDVFIVDRIKELIKYKGFQVAPAELEAILLGHPSVEDAAVVPLPDEEAGEIPAACVVLSKGAKETEDDIMKFVASNIATYKKVRVVQFVESIPKSPSGKILRRLLRDRLLEKIEKP
>evm.model.scaffold_1290.170
MEPKKEAALSQEFIFRSKLPDIYVPNHLPLHSYCFENISEFQDRPCVIDGATGKIYTYSEVELTARRVASGLHKIGIEQGHVVMLLLQNSPEFVLAFLGASYRGAMSTTANPFCTPAEIAKQATASKAKLIITRAEFAPKVKNFSEENGIYTYIYIYRHNIILTACPSRVKVMCIDTAQEGCLHFSELTQADEAEIPVVKIDPNDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFRKEDVILCVLPLFHIYSLNSVMLCGLRVGAAILIMQKFDIVRFMELVQRYKVTIAPFVPPIVLAIAKNTEVDKYDLSSIRTVMSGAAPMGKELEDSVRAKLPNAKLGQGYGMTEAGPLLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPDTGASLPRNQAGEICIRGNQIMKGYLNDPEATERTIDKQGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLISHPDISDAAVVPMKDEAAGEVPVAFIVRSNGSKITEDEIKQYISKQVVFYKRIKRVFFIEAIPKAPSGKILRKDLRARLASGVYA
>evm.model.scaffold_983.330
MEKSGYGRDGIFRSLRPPLVLPKEPNLSMVSFLFKNSISFPDKPALIDADTDETLTFSQFKSAVVKVSHGLLHLGIKKNDVVLILAPNSIQFPVCFLGITAIGAIATTSNPLYTAAELSKQAKDSRPKMLITIPELWDKVKDFNLPSVFLGSKDFSHIKSTSRVLGFQDLINLSPTSSDFPAVSVRQTDTAVLLYSSGTTGTSKGVILTHRNFIATSLMINMDQELAGEMHNVFLCVLPMFHVFGLAVISFSRLTAGNLVVSIGKFEFESFLRAVEKYRVTDLWIVPPIVLALAKQSAVKKYDLSSLRCIGSGAAPLGKDVMEECAKNFPHAAVVQGYGMTETCAIVSVENPRVGIRHTGSAGMLASGVEAQIISVDTRKPLPPNQLGEIRVRGPNMMQGYYNNPEATKLTIDSKGWVHTGDLGYFDEEGRLFVVDRIKELIKYKGFQIAPAELEGLLLSHPKILDAVVIPFPDAEAGEVPIAYVVRSPNGSLTEEDVQKFIANQVAPFKRLRKVTFIQTIPKSASGKILRRELIEKVRSRM
>evm.model.scaffold_918.129
MERSGYGRDGIFRSLRPPLVLPREPNLSMVSFLFKNSISYPDRPALIDADSGETLTFSQCKSAVAKVSHGLIHLGIKKNDVVLIFAPNSIQYPVCFLGIAAIGAIATTSNPLYTAAELSKQVKNSRPKMVITVPELWDKVKDFNIPSIFLGTADFSHIKSRSRILGFQDFMNLSPASSDFPVVSVRQTDTAALLYSSGTTGTSKGVILTHRNFIAASLMINMDQELAGEVHNVFLCVLPMFHVFGLAVISYSQLRSGNTIVSMAKFEFESALRAVEKYRVTSLWIVPPIVLALSKQQGIVKKYDLSSLRHIGSGAAPLGKDVMEDCAKSIPQAAVSQGYGMTETCGIVSVENHRVATRHTGSTGMLASGVEAQIISVGTLKPLPPKQLGEIWVRGPNMMRGYYNNPQATKLTIDREGWVHTGDLGCFDEEGQLFVVDRIKELIKYKGYQIAPAELEGLLLSHPEILDAVVIPFPDAEAGEVPIAYVVRSPSSSLTEEDVQKFIADQVAPFKRLRRVTFTQTVPKSASGKILRRELIERTAKVFREIKQRLNSFPSLRQVRRNSSASWSFPTNNNEPPPKHGTFFHPHNFLLSALTNSPLKTSRRLTMAEDKDGGEKKSGGGEEGNKEVTKSGSKAVVLKVDFHCEGCASKIIKCAKAFEGAEKVRVEWEASKLTVEGKVDPAKLRERLQEKTKKKVELVSPQLSKDKKDKKDDNTTNSSDSNKGQGNKADEKKPKELPVTTVVLKLGLHCHGCVQKIHKFVSKTSGVNSVTIERQKDLVMVTGTMDVKALVKALKGRMNREVEVIPPKQEKEKGNSNEEKKKEGSANGNGGGKMKSGGGRGGGNCGNAGGNTEEPDCVGRVDGSRMEYFGTLGHLANTGYGCSFRHGQWYTYGETVHAPQYFSDENPNACSVM
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University