Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Solanum pennellii
Species name
Solanum pennellii is a species of eudicot in the family Solanaceae (nightshade family).
Species info
Gene sequence info
Solanum_pennellii.4CL.fa
Download
>rna-XM_015209027.2
METHVVECSQKQEEGEHIFRSRYPPVHVPDNVTLPEFVLHNVELYADRLAFVDATTGKGYTYGEVERDVRRFAKALRSLGLRKGRVVLVVLPNVPEYAIVALGIMAAGGVFSGANPAAHSSEIMKQVESADGKLIVSDLPTYHKVKDCGLPVIILGEERVEGTIHWDELLEAADRASSRTDHVTNQEDEIVQQSDLCALPFSSGTTGLSKGVMLTHRNLVANLCSTLFSISPEMIGQVTILGLIPFFHIYGITGICCATIRNKGKVVVMRRYELRAFLNALITHEVSFAPIVPPIILALVKNPIVDEFDLKKLKLRSIMTAAAPLAPEILNEFEKKFPDVQVQEAYGMTEHSCITLSHCNQHIAKRNSVGFILPNLEVKFVDPDTGRSLPKNTPGEICVKSQCVMKGYYKNESETSLTIDTDGWLHTGDIGYIDDDGDIFLVDRIKELIKYKGFQVAPAELEGILLTHPSVEDTAVVGLPDEEAGEIPAAWVVLNSKAKESHEDIISYVASTVAQYKRVRLVQFVDSIPKSPSGKIMRRLIKEKMLERLKEGT
>rna-XM_015215562.2
MVSVATVDAQKAEVLSSVISTNQNQSSEELHVFRSKLPDISISNNIPLHVYLFERLSEFEERTCIIAGNSGETFTFSETYLICQKIAAGLTKVGIEKGDVIMTFLQNCSEFVFTILASSMIGAVITTANPFYTKSEAFKQLKASNAKLIVTQSQYVDKFRDPAENDPKIGEDFSVVTIDDPPENCLHFSVLSEAKAEDMPKGVVIHPDDPVALPFSSGTTGLPKGVILTHKSLITGVAQLVDGDNPNFYLKHDDVVLCVLPLFHIFALNSVLLVSLRAGASVLLMQKFEISALLELIQKHRVSVAAVVPPLVLALAKNPMVDSFDLSSIRLVLSGAAPLGKELEEALHRRVPQAIFGQGYGMTEAGPVVTMCPAFAKQPFSTKSGSCGSVVRNADLKVVDPETGGSLDRNQPGEICIRGSQIMKGYLNDDEATARTIDVDGWLHTGDIGYVDDDDEIYIVDRVKELIKFKGFQVPPAELESLLISHPDIADAAVVPQKDDAAGEVPVAFVVRSAQGFDLTEEAIKEFIAKQVVFYKKLHKVYFIHAIPKSPSGKILRKDLRAKLIATPQL
>rna-XM_015214738.2
MPMDTETNQAGDFIFRSKLPDIYIPKHLPLHSYCFENLSEFSSRPCLIDGSNDRIYTYAEVELTSRKVAVGLNKLGIQQKDTIMILLPNCPEFVFAFIGASYLGAISTMANPLFTPAEVVKQAKASSAKIVITQACFAGKVKDYAIENDLKVICVDSAPEGCFHFSELIQSDEHEIPEVNIQPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENANLYMHSDDVLMCVLPLFHIYSLNSVLLCALRVGAAILIMQKFDIAQFLELIQKHKVTIGPFVPPIVLAIAKSPLVDNYDLSSVRTVMSGAAPLGKELEDAVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFDIKSGACGTVVRNAEMKIVDPDTGCSLPRNQPGEICIRGDQIMKGYLNDPEATARTIEKEGWLHTGDIGFIDDDDELFIVDRLKELIKYKGFQVAPAELEALLVNHPNISDAAVVPMKDEQAGEVPVAFVVRSNGSTITEDEVKDFISKQVIFYKRIKRVFFVETVPKSPSGKILRKDLRARLAAGISN
>rna-XM_015224663.2
MTNVTMENETKQEDIIFRSKLPDIYIPNHLPLHSYCFENISEFKSRPCLIDGANNQIYTYADVELNSRKVAAGLHKQFGIQQKDTIMILLPNSPEFVYAFLGASYLGAISTMANPLFTSAEVVKQAKASNAKIIVTQSCHVNKVKDYALENGVNIVCIDSAPEGCVHFSELIQADEHDIPEVEIQPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHSEDVLLCVLPLFHIYSLNSVLLCGLRVGAAILIMQKFDIVPFLELIQNYKVTIGPFVPPIVLAIAKSPMVDNYDLSSVRTVMSGAAPLGKELEDTVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAQMKIVDPDTGKSLPRNQSGEICIRGDQIMKGYLNDPEATTGTIDKEGWLHTGDIGYIDNDDELFIVDRLKELIKYKGFQVAPAELEALLLNHPNISDAAVVPMKDEQAGEVPVAFVVRSNGSTITEDEVIEFITKQVIFYKRIKRVFFVDVVPKSPSGKILRKDLRAKLAAGYPN
>rna-XM_015227208.1
MEKMINKLESNYHDHNHDHDQYIFRSKLPNIYIPNHLPLHKYCFENISKFSSRTCLINSATGATYTYSDVDLAAKRIALGLHKLGIEQRDVIMILLPNSPEFVFSFLGASFRGAISTTANPFYTPSEITKQAKASNAKLIVTQSCYVDKIKCYAEENRVKIVCVDDSLPLPDGCLSFAELLLTTTHPSDENNSNDDNIILSDSVKILPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYLHSEDVIMCVLPLFHIYSLNSILLCGLRVGATILIMQKFEIKGLMELVEKYKVTIAPSVPPIVLAIAKSPLVDKYDLSSIRMIMSGAAPMGKELEDTVRAKLPNAILGQGYGMTEAGPVLSMCLAFAKQQFDVKSGSCGTVVRNAEMKIIDTNTGTLLPRNHAGEICIRGDQIMKGYLNNPKATEETIDKEGWLHTGDIGYIDDDDQVFIIDRLKELIKYKGYQVAPAELEAMLISHPNIIDAAVVPMKDEVAGEVPIAFVVKANGSNINEEEIKQYVSQQVIFYKRLNRVFFIEEIPKAPSGKILRKDLRAKLAADFAS
>rna-XM_015203391.2
MEKSGYGRDGVYRSLRPPVFYPKDENLSMVSFLFRKISSYPEKPAFFDADNGETLSFSQFKSMVSRISHGLIHQMGIKKNDVVLIFAPNSVQFPLSFFGVIAIGAIATTVNPMYTVAELSKQIKDCKPSLIITSPELFDKVNSFNLPILLLGNSNSKNAGVVRFTELVDKAGYFDLDKIVVKQTDTAVLLYSSGTTGVSKGVVLTHRNFISAALMVSSDQDLAGEMHNVYMCVLPMFHVFGLAVIMYAQLQRGNAIVSMAKFDLETLLKNIDKYRVSHLWIVPPIVLALAKNPVVKKYDLTSIKQIGSGAAPLGKDLMEDCAKNFPQAVVMQGYGMTETCGIVSVENMCVGPRHTGSAGSLAPGVEAQIVSVDKSKPLPPGQLGEIWVRGPNMMKGYFNNPQATMLTIDNQGWVHTGDLGYFTEDGLLYVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPVAYVVRSPNSSLTEEDVQKFIADQVAPFKRLKKVTFINSVPKSAAGKILRRELIDKVRSKI
>rna-XM_015204219.2
MDPNQVGDIIFKSKLPDIIIPNHLPLHTYCFQNISQFNNRPCLINGSNDQIYTYADVELTSRKVAIGLNKLGIQQKDTIMILLPNSPEFVFTFLGASYIGAISTMANPLFTQVEVMKQAKASNAKLIITQECNFNKVKDYAFENDVKVICIDGHSSSEGYLHFSDLISNSGFTSKHDHQPEVEIHPDDVVALPYSSGTTGLPKGVMLTNKGLVTSVAQQVDGENPTLFFHSEDVILCISPLFHIYALDSVLLCGLRVGATILLMKKFDVVTCLELVQKYKVTIGPFVPPIILAIAKSQVVDNYDLSSVRIVISGAAPLGKKLEEVVGIKFPNAKLGQGYGMTEAGAPITMCLAFAKEPFEIKSGACGTVIRNAEMKIVDPDTGISLPRNKPGEICIRGDQIMKGYLNDPEATKRTIDKQGWLHSGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLNLSSISDTAVVSMKDEQAGEVPVAFVVRSNGSTITEDEIKDFISKQVIFYKRIKRIFFVDVIPKSPSGKILRKDLRARLAAELPN
METHVVECSQKQEEGEHIFRSRYPPVHVPDNVTLPEFVLHNVELYADRLAFVDATTGKGYTYGEVERDVRRFAKALRSLGLRKGRVVLVVLPNVPEYAIVALGIMAAGGVFSGANPAAHSSEIMKQVESADGKLIVSDLPTYHKVKDCGLPVIILGEERVEGTIHWDELLEAADRASSRTDHVTNQEDEIVQQSDLCALPFSSGTTGLSKGVMLTHRNLVANLCSTLFSISPEMIGQVTILGLIPFFHIYGITGICCATIRNKGKVVVMRRYELRAFLNALITHEVSFAPIVPPIILALVKNPIVDEFDLKKLKLRSIMTAAAPLAPEILNEFEKKFPDVQVQEAYGMTEHSCITLSHCNQHIAKRNSVGFILPNLEVKFVDPDTGRSLPKNTPGEICVKSQCVMKGYYKNESETSLTIDTDGWLHTGDIGYIDDDGDIFLVDRIKELIKYKGFQVAPAELEGILLTHPSVEDTAVVGLPDEEAGEIPAAWVVLNSKAKESHEDIISYVASTVAQYKRVRLVQFVDSIPKSPSGKIMRRLIKEKMLERLKEGT
>rna-XM_015215562.2
MVSVATVDAQKAEVLSSVISTNQNQSSEELHVFRSKLPDISISNNIPLHVYLFERLSEFEERTCIIAGNSGETFTFSETYLICQKIAAGLTKVGIEKGDVIMTFLQNCSEFVFTILASSMIGAVITTANPFYTKSEAFKQLKASNAKLIVTQSQYVDKFRDPAENDPKIGEDFSVVTIDDPPENCLHFSVLSEAKAEDMPKGVVIHPDDPVALPFSSGTTGLPKGVILTHKSLITGVAQLVDGDNPNFYLKHDDVVLCVLPLFHIFALNSVLLVSLRAGASVLLMQKFEISALLELIQKHRVSVAAVVPPLVLALAKNPMVDSFDLSSIRLVLSGAAPLGKELEEALHRRVPQAIFGQGYGMTEAGPVVTMCPAFAKQPFSTKSGSCGSVVRNADLKVVDPETGGSLDRNQPGEICIRGSQIMKGYLNDDEATARTIDVDGWLHTGDIGYVDDDDEIYIVDRVKELIKFKGFQVPPAELESLLISHPDIADAAVVPQKDDAAGEVPVAFVVRSAQGFDLTEEAIKEFIAKQVVFYKKLHKVYFIHAIPKSPSGKILRKDLRAKLIATPQL
>rna-XM_015214738.2
MPMDTETNQAGDFIFRSKLPDIYIPKHLPLHSYCFENLSEFSSRPCLIDGSNDRIYTYAEVELTSRKVAVGLNKLGIQQKDTIMILLPNCPEFVFAFIGASYLGAISTMANPLFTPAEVVKQAKASSAKIVITQACFAGKVKDYAIENDLKVICVDSAPEGCFHFSELIQSDEHEIPEVNIQPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENANLYMHSDDVLMCVLPLFHIYSLNSVLLCALRVGAAILIMQKFDIAQFLELIQKHKVTIGPFVPPIVLAIAKSPLVDNYDLSSVRTVMSGAAPLGKELEDAVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFDIKSGACGTVVRNAEMKIVDPDTGCSLPRNQPGEICIRGDQIMKGYLNDPEATARTIEKEGWLHTGDIGFIDDDDELFIVDRLKELIKYKGFQVAPAELEALLVNHPNISDAAVVPMKDEQAGEVPVAFVVRSNGSTITEDEVKDFISKQVIFYKRIKRVFFVETVPKSPSGKILRKDLRARLAAGISN
>rna-XM_015224663.2
MTNVTMENETKQEDIIFRSKLPDIYIPNHLPLHSYCFENISEFKSRPCLIDGANNQIYTYADVELNSRKVAAGLHKQFGIQQKDTIMILLPNSPEFVYAFLGASYLGAISTMANPLFTSAEVVKQAKASNAKIIVTQSCHVNKVKDYALENGVNIVCIDSAPEGCVHFSELIQADEHDIPEVEIQPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHSEDVLLCVLPLFHIYSLNSVLLCGLRVGAAILIMQKFDIVPFLELIQNYKVTIGPFVPPIVLAIAKSPMVDNYDLSSVRTVMSGAAPLGKELEDTVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAQMKIVDPDTGKSLPRNQSGEICIRGDQIMKGYLNDPEATTGTIDKEGWLHTGDIGYIDNDDELFIVDRLKELIKYKGFQVAPAELEALLLNHPNISDAAVVPMKDEQAGEVPVAFVVRSNGSTITEDEVIEFITKQVIFYKRIKRVFFVDVVPKSPSGKILRKDLRAKLAAGYPN
>rna-XM_015227208.1
MEKMINKLESNYHDHNHDHDQYIFRSKLPNIYIPNHLPLHKYCFENISKFSSRTCLINSATGATYTYSDVDLAAKRIALGLHKLGIEQRDVIMILLPNSPEFVFSFLGASFRGAISTTANPFYTPSEITKQAKASNAKLIVTQSCYVDKIKCYAEENRVKIVCVDDSLPLPDGCLSFAELLLTTTHPSDENNSNDDNIILSDSVKILPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYLHSEDVIMCVLPLFHIYSLNSILLCGLRVGATILIMQKFEIKGLMELVEKYKVTIAPSVPPIVLAIAKSPLVDKYDLSSIRMIMSGAAPMGKELEDTVRAKLPNAILGQGYGMTEAGPVLSMCLAFAKQQFDVKSGSCGTVVRNAEMKIIDTNTGTLLPRNHAGEICIRGDQIMKGYLNNPKATEETIDKEGWLHTGDIGYIDDDDQVFIIDRLKELIKYKGYQVAPAELEAMLISHPNIIDAAVVPMKDEVAGEVPIAFVVKANGSNINEEEIKQYVSQQVIFYKRLNRVFFIEEIPKAPSGKILRKDLRAKLAADFAS
>rna-XM_015203391.2
MEKSGYGRDGVYRSLRPPVFYPKDENLSMVSFLFRKISSYPEKPAFFDADNGETLSFSQFKSMVSRISHGLIHQMGIKKNDVVLIFAPNSVQFPLSFFGVIAIGAIATTVNPMYTVAELSKQIKDCKPSLIITSPELFDKVNSFNLPILLLGNSNSKNAGVVRFTELVDKAGYFDLDKIVVKQTDTAVLLYSSGTTGVSKGVVLTHRNFISAALMVSSDQDLAGEMHNVYMCVLPMFHVFGLAVIMYAQLQRGNAIVSMAKFDLETLLKNIDKYRVSHLWIVPPIVLALAKNPVVKKYDLTSIKQIGSGAAPLGKDLMEDCAKNFPQAVVMQGYGMTETCGIVSVENMCVGPRHTGSAGSLAPGVEAQIVSVDKSKPLPPGQLGEIWVRGPNMMKGYFNNPQATMLTIDNQGWVHTGDLGYFTEDGLLYVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPVAYVVRSPNSSLTEEDVQKFIADQVAPFKRLKKVTFINSVPKSAAGKILRRELIDKVRSKI
>rna-XM_015204219.2
MDPNQVGDIIFKSKLPDIIIPNHLPLHTYCFQNISQFNNRPCLINGSNDQIYTYADVELTSRKVAIGLNKLGIQQKDTIMILLPNSPEFVFTFLGASYIGAISTMANPLFTQVEVMKQAKASNAKLIITQECNFNKVKDYAFENDVKVICIDGHSSSEGYLHFSDLISNSGFTSKHDHQPEVEIHPDDVVALPYSSGTTGLPKGVMLTNKGLVTSVAQQVDGENPTLFFHSEDVILCISPLFHIYALDSVLLCGLRVGATILLMKKFDVVTCLELVQKYKVTIGPFVPPIILAIAKSQVVDNYDLSSVRIVISGAAPLGKKLEEVVGIKFPNAKLGQGYGMTEAGAPITMCLAFAKEPFEIKSGACGTVIRNAEMKIVDPDTGISLPRNKPGEICIRGDQIMKGYLNDPEATKRTIDKQGWLHSGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLNLSSISDTAVVSMKDEQAGEVPVAFVVRSNGSTITEDEIKDFISKQVIFYKRIKRIFFVDVIPKSPSGKILRKDLRARLAAELPN
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University