Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Sisymbrium irio
Species name
Sisymbrium irio is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Sisymbrium_irio.4CL.fa
Download
>SI_scaffold25_82.mRNA1
MEKSGYGRDGIYRSLRPTLVLPEDPNTTLVSLLFRNTSSYPSKPALVDSDSGHSLSFSQLKSAVSRLAHGFLRLGIRKNDVVLIFAPNSYQFPLCFLAVTAIGGVFTTVNPAYTVNEVSKQVKDCNPKVIISVKELLDKVKPFDLPIVLLGSDESVVQSLDSNSNIISFKNVMELSEPVSDLPSVDVKQTDTAALLYSSGTTGMSKGVELTHGNFIAAALMVTMDQDLMGEYHGVFLCFLPMFHVFGLNVVSYAQLQRGNTVISMAKFELERLLQNIEKYRVTQLWVVPPVFLALAKQSIVKKYDLSSLKYIGSGAAPLGKDLMEECARNIPNVVLLQGYAMTETTGIVSMEDPRLGKRNSGSCGRLASGVDAQVVSVESGKPQPPNQKGEIWVRGRNMMKGYLNNPQATKETIDENGWVHTGDLGYFNEDGNLFVVDRIKELIKCNGFQVAPAELEGLLVSHPELLDAVVIPFPDVKAGEVPIAFVVRSPNSSIVEEDIQKFIAKQVAPYKRLRRVSFINSVPKSAAGKILRRELVQQVRSKM
>SI_scaffold25_83.mRNA1
MEKSGYGRDGIYRSLRPKLVLPKDPNTSLVTFLFRNSSSYPSKPALIDSDTGDSLSFSQLKSSVARLAQGFLRLGIRKNDVVLIFAPNSYQFPLCFLAVTAIGGVFTTANPLYTTNEVSKQVKDSNPKIIISVEQLFDKVKDFNLPIVLLGSVESCLDSKRILFESKIITFKNVMELSDTVSDLPVVDVKQSDTAALLYSSGTTGVSKGVELTHGNFIAAAMMVTMDQDLIGEYHGVFLCFLPMFHVFGLAVIAYSQLQRGSALVSMARFELETLLKNIEKYRVTQLWVVPPVFLALSKQSIVKKYDLSSLKYIGSGAAPLGKDLMEECGKNIPNVVLMQGYGMTETCGIVSVEDPRLGKRNSGSAGMLAPGVEAQIVSVETGKSQPPNQQGEIWVRGANMMKGYFNNPQATKETIDKKGWVHTGDLGYFNEDGNLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDEEAGEVPIAFVVRSPSSSITEEDIQKFIAKQVAPYKRLRRVSFISTVPKSAAGKILRRELIQQVRSKM
>SI_scaffold95_27.mRNA1
MITAAQHEPQIHKPVDTTSPTVVSTDAASPTPRIFRSKLPDIDIPNHLPLHTYCFEKLSSVSDKPCLLVGSTGKSYTYGETHLLCRRVAAGLYKMGIRKGDVIMILLQNSAEFVFSFMGASMIGAISTTANPFYTSQEIHKQVISSGVKLIITHSHYVDKLRSLDEESKIGEDLTVITTEDPTPENCLSFSTLLTDKTNPQDEQESVNVGGDDAAALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGENPNLYMRSNDVVLCVLPLFHIYSLNSVLLNSIRTGATVLLMHKFEIMSLLDLIQRHKVTIAALVPPLVIALAKNPAVNSYDLSSVRLVLSGAAPLGKDLEDSLRCRLPQAVLGQIPLNINGRGMHGKRVRSVASSSSA
>SI_scaffold95_28.mRNA1
MNKQGYGMTEAGPVLSMSLGFAKEPIPSKSGSCGTVVRNAELKVVHLETHISLGYNQSGEICIRGQQIMKEYLNDPEATSATIDEEGWLHTGDIGYVDEDDEIFIVDRLKEVIKFKGFQASPLLLFES
>SI_scaffold965_20.mRNA1
MRSDVGYEQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAELKIIDPDTGSSLSRNNSGEICIRGHQIMKGYLNDPAATAATIDKDGWLHTGDIGFVDDDDELFIVDRLKELIKYKGFQVAPAELESLLISHSDINDVAVVAMREEDAGEVPVAFVVRSKGSNISEDEIKQFVSKQVVFYKRINKVFFIDSIPKAPSGKILRKDLRARLANESMEPSLK
>SI_scaffold965_23.mRNA1
MVLQQEQQTPSLTKKIDQELSHEFIFRSKLPDISIPSHLPLTEYVFQKLSGDGDGDSTSTCLIDGATGRIFTYADVQINLRRIAAGIHRLGIRQGDTVMLLLPNSPEFALSFLAVAYLGAVSTTANPFYTHAEIAKQAKASATKMIITKRCYVDKLTNLKDGGVLIVCVDDENDVVSAEEGCVSFTELTQADETELPKPEISPEDTVSMPYSSGTTGLPKGVMITHKGLVTSIAQKVDGENPNVNFTKDDVILCFLPMFHIYALDALMLSAMRTGAAILIVPRFELNLVMELIQRYKVTVVPVAPPVVLALVKSPETERYDLSSVRLMLSGAATLKKELEDAVRLKFPNAIFGQLIKHRESTMISFVMDLGSHTLTHDNVKKNHFDPIAHFIQHFLVWFLTFLCCFYIMYYESNSINQKWTVLSFETNELSAQGYGMTESGTVAKSLAFAKNPFQTKSGACGTVIRNAEMKVVDTITGVSLPRNKPGEICIRGDQLMKGYLNDPEATAQTIDKDGWLHTGDIGFVDDDDEIFIVDRLKELIKFKGYQVAPAELEALLISHPYIEDAAVVAMKDEVADEVPVAFVVKSEGSQLTEDDVKSYVNKQVVHYKRIKMVFFIEAIPKAVSGKILRKELRAKLETEYPK
>SI_scaffold965_19.mRNA1
MSTQEATITDQKQSSAADVIFRSKLPDIYIPNHLPLHDYIFQNISEFAAKPCLINGPTGQVYSYADVHATSRKLSAGLSKLGVEKHDVVMLLLPNSPEFVFTFFATSFLGAVTTAANPFFTPAEISKQAKASAVKLIVTHSRYVDKVRDLGVLIICTDEESSSAIPEGCLRFSELTLPGDEDHHSAAEISPEDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENSNLYFNKEDVILCVLPMFHIYALNSIMLCSLRVGATILIMPKFEISLLLEQIQRCKVTVAMVVPPIVLAMVKSSETEKYDLSSVRMIKSGAAPLGKELEDAVSAKFPNAKLGQLVLLRISYHDYMSDSY
>SI_scaffold965_22.mRNA1
MVLLKQQTLSVTKKIDQEPSHEFIFRSKLPDISIPSHLPLTEYVFQKFSSDGDGDSTTTCLIDGANGRIFTYADVQITLRRIAAGIHRLGIGHGDTVMLLLPNSPEFSLSFLAVAYLGAVSTTANPLYTQSEILKQAKASATKMIITKRCYVDKLRNLQNLGVFIVCVDDGHDVVSLADGCVSFTELAQADERELPKPEISPEDTLSIPYSSGTTGLPKGVMITHKGLVTSIAQKVDGENPNLNFSGDDVIICFLPMFHTYTHNSLMLSAMRTGAATLIMPRFQLNLVMEMIQKYKVTVVPVAPPVVLAFVKSQETERYDLSSVRMMLSGAAVLKKELEDAVRLKLPNAIFGQSYGMTEAGTVANSLAFAKNPFRTKSGTCGTVIRNAEMKVVDTITGVSLPRNKPGEICIRGDQLMKGNARATARAIDKDGWLHTGDIGFVDDDDEIFIVDRLKELIKFKGYQVAPAELEALLISHPYIEDAAVVAMKDEVANEVPVACVVKSEGSQLTGDDVKNYVNKQVVHYKRIKMVFFVKAIPKSASGKLLRKELRAKL
>SI_scaffold965_21.mRNA1
MLLQQEQQTLFLTKKSDEERPSHDFIFRSKLPDISIPSHLPLTEYVFQKFSGDGDGDSTTTCLIDGATGRIFTYADVQINMRRIAAGIHRLGISHGDTVMLLLPNSPEFALSFLANAYLGAISTTANPFYTQAEIAKQFNASGAKMIITKRCYVDKLTNLQNVLIVCVDDAVSSDDGCVSFTELTQADETVLPKVEISPDDTVAIPYSSGTTGLPKGVMVTHKGLVTSIAQRVDGENPNLNFTGDDVIICFLPMFHTYAFNALILSAMRTGAAILIVLRFELNLVMELIQKYKVTVLPVAPPVVLAFAKSPETERYDLSSVRLMISAAATLRKELEDAVRLKFPNAVLSQCYGMTESGSVAVSLAFAKNPFRTKSGACGTVIRNSEMKVVDTITGVSLPRNKPGEICIRGDQLMKGYLNDPEATARTIDKDGWLHTGDIGFVDDDDEIFIVDRLKELIKFKGYQVAPAELEALLISHHYIEDAAVVAMKDDVAGEIPVAFVVRSQGSQLTENDVTSYVNKQVIHYKRIKMVFFTDSIPKAPSGKILRKDLRERLANGSMNITT
>SI_scaffold1129_13.mRNA1
MAPQEEVMQKQSSSNSDIIYRSKLPDIYIPNHLPLHDYIFQNISEFASKPCLINGPTGHVYTYTDVHVASRQIASGFQKLGVDRNDVVMILLSNCPEFVLSFLGASFRGATATAANPFFTPAEIAKQAKASNTKLIVTESRYVDKIKDLQNDGVIIVCTDGESSPIPEGCLRFTELTQSTEIETVEISSDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHSDDVILCVLPMFHIYALNSIMLCGLRVGAAILIMPKFEINLLLELVQRCKVTVAPMVPPIVLAIAKSPETEKYDLSSIRVVKSGAAPLGKELEDAVSAKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKIVDPDTGNSLPKNQPGEICIRGHQIMKGYLNNPEATAETIDKDGWLHTGDIGLIDEDDELFIVDRLKELIKYKGFQVAPAELEALLIGHPDITDVAVVAMKDEAAGEVPVAFVVKSKDSELSEDDVKQFVSKQVVFYKKINKVFFADSIPKAPSGKILRKDLRAKLANELVN
>SI_scaffold1632_12.mRNA1
MECQKQDNEYIFRSLYPSVPIPDKLTLPEFVLQGVEEFTENLAFVEAVTGKAVTYGDVVRDTKRLAKALTSLGLRKGQVMVVVLPNVAEYGIIALGIMSAGGVFSGANPTALVSEIKKQVEASGARGIITDSTNYEKVRFGTSNYFFRYIFRFEVKTLGLPVIVLGEEKIEGAVNWKDLLDAGDKSGDNNREEILQTDLCALPFSSGTTGLQKGVMLTHRNLIANLCSSLFSVRSEMIGQIVTLGLIPFFHIYGIVGICCATMKNKGKVVAMSRYDLRLFLNALIAHEVSFAPIVPPIILNLVKNPIVDEFDLSKLKLRSVMTAAAPLAPELLTAFEAKFPNVQVQEASVKDLRGFSSVLAYGLTEHSCITLTHGDPDKGQGIAKRNSVGFILPNLEVKFIDPDTGRSLPKNTSGELCVRSQCVMQGYFKNKEETEKTIDEEGWLHTGDVGYIDDDGDIFIVDRIKELIKYKGFQVAPAELEAILLTHPSVEDVAVVPLPDEEAGEIPVACVVMNPKAKEKEEDILSFVAANVAHYKKIRAVHFVESIPKSLSGKIMRRLLRDKILSMKKTSF
MEKSGYGRDGIYRSLRPTLVLPEDPNTTLVSLLFRNTSSYPSKPALVDSDSGHSLSFSQLKSAVSRLAHGFLRLGIRKNDVVLIFAPNSYQFPLCFLAVTAIGGVFTTVNPAYTVNEVSKQVKDCNPKVIISVKELLDKVKPFDLPIVLLGSDESVVQSLDSNSNIISFKNVMELSEPVSDLPSVDVKQTDTAALLYSSGTTGMSKGVELTHGNFIAAALMVTMDQDLMGEYHGVFLCFLPMFHVFGLNVVSYAQLQRGNTVISMAKFELERLLQNIEKYRVTQLWVVPPVFLALAKQSIVKKYDLSSLKYIGSGAAPLGKDLMEECARNIPNVVLLQGYAMTETTGIVSMEDPRLGKRNSGSCGRLASGVDAQVVSVESGKPQPPNQKGEIWVRGRNMMKGYLNNPQATKETIDENGWVHTGDLGYFNEDGNLFVVDRIKELIKCNGFQVAPAELEGLLVSHPELLDAVVIPFPDVKAGEVPIAFVVRSPNSSIVEEDIQKFIAKQVAPYKRLRRVSFINSVPKSAAGKILRRELVQQVRSKM
>SI_scaffold25_83.mRNA1
MEKSGYGRDGIYRSLRPKLVLPKDPNTSLVTFLFRNSSSYPSKPALIDSDTGDSLSFSQLKSSVARLAQGFLRLGIRKNDVVLIFAPNSYQFPLCFLAVTAIGGVFTTANPLYTTNEVSKQVKDSNPKIIISVEQLFDKVKDFNLPIVLLGSVESCLDSKRILFESKIITFKNVMELSDTVSDLPVVDVKQSDTAALLYSSGTTGVSKGVELTHGNFIAAAMMVTMDQDLIGEYHGVFLCFLPMFHVFGLAVIAYSQLQRGSALVSMARFELETLLKNIEKYRVTQLWVVPPVFLALSKQSIVKKYDLSSLKYIGSGAAPLGKDLMEECGKNIPNVVLMQGYGMTETCGIVSVEDPRLGKRNSGSAGMLAPGVEAQIVSVETGKSQPPNQQGEIWVRGANMMKGYFNNPQATKETIDKKGWVHTGDLGYFNEDGNLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDEEAGEVPIAFVVRSPSSSITEEDIQKFIAKQVAPYKRLRRVSFISTVPKSAAGKILRRELIQQVRSKM
>SI_scaffold95_27.mRNA1
MITAAQHEPQIHKPVDTTSPTVVSTDAASPTPRIFRSKLPDIDIPNHLPLHTYCFEKLSSVSDKPCLLVGSTGKSYTYGETHLLCRRVAAGLYKMGIRKGDVIMILLQNSAEFVFSFMGASMIGAISTTANPFYTSQEIHKQVISSGVKLIITHSHYVDKLRSLDEESKIGEDLTVITTEDPTPENCLSFSTLLTDKTNPQDEQESVNVGGDDAAALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGENPNLYMRSNDVVLCVLPLFHIYSLNSVLLNSIRTGATVLLMHKFEIMSLLDLIQRHKVTIAALVPPLVIALAKNPAVNSYDLSSVRLVLSGAAPLGKDLEDSLRCRLPQAVLGQIPLNINGRGMHGKRVRSVASSSSA
>SI_scaffold95_28.mRNA1
MNKQGYGMTEAGPVLSMSLGFAKEPIPSKSGSCGTVVRNAELKVVHLETHISLGYNQSGEICIRGQQIMKEYLNDPEATSATIDEEGWLHTGDIGYVDEDDEIFIVDRLKEVIKFKGFQASPLLLFES
>SI_scaffold965_20.mRNA1
MRSDVGYEQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAELKIIDPDTGSSLSRNNSGEICIRGHQIMKGYLNDPAATAATIDKDGWLHTGDIGFVDDDDELFIVDRLKELIKYKGFQVAPAELESLLISHSDINDVAVVAMREEDAGEVPVAFVVRSKGSNISEDEIKQFVSKQVVFYKRINKVFFIDSIPKAPSGKILRKDLRARLANESMEPSLK
>SI_scaffold965_23.mRNA1
MVLQQEQQTPSLTKKIDQELSHEFIFRSKLPDISIPSHLPLTEYVFQKLSGDGDGDSTSTCLIDGATGRIFTYADVQINLRRIAAGIHRLGIRQGDTVMLLLPNSPEFALSFLAVAYLGAVSTTANPFYTHAEIAKQAKASATKMIITKRCYVDKLTNLKDGGVLIVCVDDENDVVSAEEGCVSFTELTQADETELPKPEISPEDTVSMPYSSGTTGLPKGVMITHKGLVTSIAQKVDGENPNVNFTKDDVILCFLPMFHIYALDALMLSAMRTGAAILIVPRFELNLVMELIQRYKVTVVPVAPPVVLALVKSPETERYDLSSVRLMLSGAATLKKELEDAVRLKFPNAIFGQLIKHRESTMISFVMDLGSHTLTHDNVKKNHFDPIAHFIQHFLVWFLTFLCCFYIMYYESNSINQKWTVLSFETNELSAQGYGMTESGTVAKSLAFAKNPFQTKSGACGTVIRNAEMKVVDTITGVSLPRNKPGEICIRGDQLMKGYLNDPEATAQTIDKDGWLHTGDIGFVDDDDEIFIVDRLKELIKFKGYQVAPAELEALLISHPYIEDAAVVAMKDEVADEVPVAFVVKSEGSQLTEDDVKSYVNKQVVHYKRIKMVFFIEAIPKAVSGKILRKELRAKLETEYPK
>SI_scaffold965_19.mRNA1
MSTQEATITDQKQSSAADVIFRSKLPDIYIPNHLPLHDYIFQNISEFAAKPCLINGPTGQVYSYADVHATSRKLSAGLSKLGVEKHDVVMLLLPNSPEFVFTFFATSFLGAVTTAANPFFTPAEISKQAKASAVKLIVTHSRYVDKVRDLGVLIICTDEESSSAIPEGCLRFSELTLPGDEDHHSAAEISPEDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENSNLYFNKEDVILCVLPMFHIYALNSIMLCSLRVGATILIMPKFEISLLLEQIQRCKVTVAMVVPPIVLAMVKSSETEKYDLSSVRMIKSGAAPLGKELEDAVSAKFPNAKLGQLVLLRISYHDYMSDSY
>SI_scaffold965_22.mRNA1
MVLLKQQTLSVTKKIDQEPSHEFIFRSKLPDISIPSHLPLTEYVFQKFSSDGDGDSTTTCLIDGANGRIFTYADVQITLRRIAAGIHRLGIGHGDTVMLLLPNSPEFSLSFLAVAYLGAVSTTANPLYTQSEILKQAKASATKMIITKRCYVDKLRNLQNLGVFIVCVDDGHDVVSLADGCVSFTELAQADERELPKPEISPEDTLSIPYSSGTTGLPKGVMITHKGLVTSIAQKVDGENPNLNFSGDDVIICFLPMFHTYTHNSLMLSAMRTGAATLIMPRFQLNLVMEMIQKYKVTVVPVAPPVVLAFVKSQETERYDLSSVRMMLSGAAVLKKELEDAVRLKLPNAIFGQSYGMTEAGTVANSLAFAKNPFRTKSGTCGTVIRNAEMKVVDTITGVSLPRNKPGEICIRGDQLMKGNARATARAIDKDGWLHTGDIGFVDDDDEIFIVDRLKELIKFKGYQVAPAELEALLISHPYIEDAAVVAMKDEVANEVPVACVVKSEGSQLTGDDVKNYVNKQVVHYKRIKMVFFVKAIPKSASGKLLRKELRAKL
>SI_scaffold965_21.mRNA1
MLLQQEQQTLFLTKKSDEERPSHDFIFRSKLPDISIPSHLPLTEYVFQKFSGDGDGDSTTTCLIDGATGRIFTYADVQINMRRIAAGIHRLGISHGDTVMLLLPNSPEFALSFLANAYLGAISTTANPFYTQAEIAKQFNASGAKMIITKRCYVDKLTNLQNVLIVCVDDAVSSDDGCVSFTELTQADETVLPKVEISPDDTVAIPYSSGTTGLPKGVMVTHKGLVTSIAQRVDGENPNLNFTGDDVIICFLPMFHTYAFNALILSAMRTGAAILIVLRFELNLVMELIQKYKVTVLPVAPPVVLAFAKSPETERYDLSSVRLMISAAATLRKELEDAVRLKFPNAVLSQCYGMTESGSVAVSLAFAKNPFRTKSGACGTVIRNSEMKVVDTITGVSLPRNKPGEICIRGDQLMKGYLNDPEATARTIDKDGWLHTGDIGFVDDDDEIFIVDRLKELIKFKGYQVAPAELEALLISHHYIEDAAVVAMKDDVAGEIPVAFVVRSQGSQLTENDVTSYVNKQVIHYKRIKMVFFTDSIPKAPSGKILRKDLRERLANGSMNITT
>SI_scaffold1129_13.mRNA1
MAPQEEVMQKQSSSNSDIIYRSKLPDIYIPNHLPLHDYIFQNISEFASKPCLINGPTGHVYTYTDVHVASRQIASGFQKLGVDRNDVVMILLSNCPEFVLSFLGASFRGATATAANPFFTPAEIAKQAKASNTKLIVTESRYVDKIKDLQNDGVIIVCTDGESSPIPEGCLRFTELTQSTEIETVEISSDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHSDDVILCVLPMFHIYALNSIMLCGLRVGAAILIMPKFEINLLLELVQRCKVTVAPMVPPIVLAIAKSPETEKYDLSSIRVVKSGAAPLGKELEDAVSAKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKIVDPDTGNSLPKNQPGEICIRGHQIMKGYLNNPEATAETIDKDGWLHTGDIGLIDEDDELFIVDRLKELIKYKGFQVAPAELEALLIGHPDITDVAVVAMKDEAAGEVPVAFVVKSKDSELSEDDVKQFVSKQVVFYKKINKVFFADSIPKAPSGKILRKDLRAKLANELVN
>SI_scaffold1632_12.mRNA1
MECQKQDNEYIFRSLYPSVPIPDKLTLPEFVLQGVEEFTENLAFVEAVTGKAVTYGDVVRDTKRLAKALTSLGLRKGQVMVVVLPNVAEYGIIALGIMSAGGVFSGANPTALVSEIKKQVEASGARGIITDSTNYEKVRFGTSNYFFRYIFRFEVKTLGLPVIVLGEEKIEGAVNWKDLLDAGDKSGDNNREEILQTDLCALPFSSGTTGLQKGVMLTHRNLIANLCSSLFSVRSEMIGQIVTLGLIPFFHIYGIVGICCATMKNKGKVVAMSRYDLRLFLNALIAHEVSFAPIVPPIILNLVKNPIVDEFDLSKLKLRSVMTAAAPLAPELLTAFEAKFPNVQVQEASVKDLRGFSSVLAYGLTEHSCITLTHGDPDKGQGIAKRNSVGFILPNLEVKFIDPDTGRSLPKNTSGELCVRSQCVMQGYFKNKEETEKTIDEEGWLHTGDVGYIDDDGDIFIVDRIKELIKYKGFQVAPAELEAILLTHPSVEDVAVVPLPDEEAGEIPVACVVMNPKAKEKEEDILSFVAANVAHYKKIRAVHFVESIPKSLSGKIMRRLLRDKILSMKKTSF
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University