Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Sesamum indicum
Species name
Sesame (Sesamum indicum) is a species of eudicot in the family Pedaliaceae (sesame family).
Species info
Gene sequence info
Sesamum_indicum.4CL.fa
Download
>rna-XM_011084443.2
MATATKQKDIIFRSKLPDIYIPNHLPLHSYCFQNISQFSTRPCLINGSTDDVYTYEEVELVSRRVAAGLSKLGIRKGDTIMILLPNSPEFVFAFLGASYIGAVSTTANPFFTPAEVAKQAKASIAKLIITQACYVEKVREYGRENGVKVVCVDTPPAGSGCLEFSQLTSADKKEMPAVEIKPEDTVALPYSSGTTGLPKGVMLTHKGLVTNVAQHVDGENPNLYIHSEDVVLCLLPLFHIYSLSVMLCGLRVGAAILIMQKFDIVPLLELIQKYKVTIGPFVPPIVLDIAKSPVVGKYDLSSVRTVMSGAAPLGKELEDAVRIKFPNAKLGQGYGMTEAGAVLAMCLAFAKEPFEIKSGACGTVVRNAEMKILDPETGASLPRNQPGEICIRGDQIMKGYLNDPEATERTIDKEGWLHTGDIGFIDDDDELFIVDRLKEIIKYKGFQVAPAELEALLLNHPYIADAAVVPMKDEMKHEKTGEVPVAFVVKSKGSTMSEDEIKEFISKQVIFYKRIKRVFFMEAIPKSPSGKILRKDLRARLPAFSN
>rna-XM_011071601.2
MELEEHIFRSKLPDIYIPNHLPTHVYCFENLSNHRLRPALINGPTGEVFTHADVELTARRVAVGLHNLGIRKNHVIMLLLHNSPEFAFAFLASSFVGAAATTANPLYTAAEITLQAKISKPKLIITHACYVGKVEHFAFEEGAKIVTIDPPPSPLIIHLSELTRSDEKLLPEVEIQAEDMPALPFSSGTTGFPKGVMLSHKNLVTCVSQQVDGENPAFHLDVKDLTVCVLPLFHVYSLITVLLCSLRAGAAVLILPKYEINALMELIQKYRVTIAPFVPPILLAIAKIPAAAAGKFDLSSVRRVTCGAAPMDKQLEGAVKCKLPNAMIGQGYGMTEAGVLTMCLGFAKRPFRFKPGSCGTVIRNARMKVIDPSTGVSLPRNQTGEICIRGDAVMKGYYNEPEATKRTVDKEGWLHTGDIGYVDDDDEVFIVDRLKELIKYKGFHIAPAELEALLIAHPSISDAAVVPMRDEGAGEVPVAFVVPANGSSITQQEVKQYISKQVVSYKRINRVFFIDEIPKAPSGKILRKKLRARI
>rna-XM_011074951.2
MEPVTKQDDVVFRSKLPDIYIPKHLPLHSYCFENMPKFSSRPCLINGATDEVYTYEEVELTSRKVXXXXXXGDTIMLLLPNSPEFVFAFLGASYIGAISTMANPFFTPGEVIKQAKASNAKLIITQACYVEKVRDYASEKGVKVMCVDAPPSDCLKFSELTLADERDMPAVKIHPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHSEDVMLCVLPLFHIYSLNSVLLCGLRVGAAILIMQKFDIVPFLELIQKYRVTIGPFVPPIVLAIAKSPLVDKYDLSSVRTVMSGAAPLGKELEDAVRIKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDTETGQSLGRNQPGEICIRGDQIMKGYLNDPESTERTIDKEGWLHTGDIGFIDADDELFIVDRLKEIIKYKGFQVAPAELEALLLNHPYISDAAVVPMKDEQAGEVPVAFVVKSNGSNITEDEIKQFVSKQVVFYKRINRVFFIESIPKSPSGKILRKDLRARLAAGIPN
>rna-XM_011086311.2
MLSVASVETQNPELSSSLVLPQNQTSETHVFVSKLPAIPISNHLPLHTYCFENLSQYPDRSCLLVGSTGKSYSFAETHLVCRKVAAGLSNLGIRKGDVVMALLQNCAEFVFTFMGASMIGAVTTTANPFCTTKEIFKQFNASKSKVIITQSQYVDKLRDPGDSSLVFGEDFSVITIDSPPEGCLHFSVLSEANENEAPEVEIDPDDAVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNLYLKPDDVVLCVLPLFHIYSLNSVLLCSLRAGAPVLLMQKFEIGSLLELIQRHRVSVAAVVPPLVLALAKNPLVDNFDLSSIRMVLSGAAPLGKELEAALLSRVPQAVFGQGYGMTEAGPVLSMSPAFAKQPLPTKSGSCGNVVRNAELKVVDPETGCSLPRNHPGEICIRGPQIMKGYLNDAEATARTIDVDGWLHTGDIGYVDDDDDVFIVDRVKELIKFKGFQVPPAELEALLISHPNIADAAVVPQKDEAAGEVPVAFVVRSNGFELTEEAVKEFISKQVVFYKRLHKVYFVHAIPKSPAGKILRKDLRAKLAAAAPSSTS
>rna-XM_011088970.2
MKLKTCMHVMNMLTGSFTARFSSTSAAGHFSARNRSWFLFQPPACAFQNKLRICMMPLKYHVSTFNFRAMQTETTPTPLLYSEDGIHRSPRPPIFLPNLSMISFLFRKLPSNAHSPALIQAETGQTLTFSDLKTQVFNFSKTLLDFNISKNDVVLIISPNSLLFPVAIFAVVAVGAIATTANPLCTAAEISKQVKDSNPKLIITTPQLHDKIKHLNLPCIMLATSKIPIYSSTTSSNSTWYYSHSDTFSSDIALPPVMQTDVAAILYSSGTTGTSKGVVLTHRNFIASALMMTSDQESYGDSRNVFLCFLPMFHIFGLSALLYAQLQRGNTVVVMARHEMKKMLSAVEKYKVTHLWVVPPVVVELAKHQEMVKEYDISSVREILSGAAPLGKETAEECARIFPDAVVYQGYGMTETGGPISFGNVRTDTPYSGSTGVLAPGVEAQIVNLGTMKPLPPLRRGEIWVRGLMVMQGYFNNQKATMETIDEQGWLHTGDIGYFDEKGRLYVVDRVKELIKCNGYQVAPAELEELLLTHPEIKDAAVIGLADAEVGEVPIAYVVRSSTTSLVEEEVKTFIAEQVAAYKRLRRVIFTDSIPKSASGKILRKELAQRFLSKL
>rna-XM_011088853.2
MPSQLIYGNDGIYRSPRPPLSLPQDPKFSMIPYLFRNLSSISHLPALVDAETGQTSTFSVLRTQVLNFSKALLDLSVSKNDVVLIISPNSLLFPVAFFAVVAIGAIATTANPLYTAAEISKQVKDSDPKLIITIPPLYDKIKHLNLPCIMLTNSTTPSNSNWYNSSDFINKTSLNVLLSDSDFPPVHQDDPAAILYSSGTTGASKGVVLSHKNFIATSMMVTSDQDQAYGEAKNVFLCFLPMFHISGLVAVLFAQLQRGNKVVVMPRYEMEKMLRTIEKYKVSHFFAAPPVIVALAKNQEVVKKYDVSSLREIGSGAAPLGKDVLEECAKVFPQTALYQGYGLTETCGAVSLENAAASSQHSGSTGMLDPGVEARIMDLERMQPLPPLQKGEIWVRGPNVMLGYFKNEKATKETIDDEGWLHTGDLGYFDNEGRIHVVDRLKELIKYKGFQVAPAELEELLLTHPEIKDAAVIGLSDVDAGEVPIAFVVRSSYSSLTEVETKDFIAKQVAPYKRLRKVIFSEEIPKSAAGKILRRELRHRFLSKL
>rna-XM_011090937.2
MEKSGYGRDGVYRSLRPPLFLPKDPNLSMVSFLFRNASSFADKPALIDSHTGKILTFAQFKSMVSRVSHGLLQLGIKKNDIVLIYAPNSIQYPLCFFGIVAIGAVATTVNPIYTVSELSKQVQDSKAKLIITVEDLLPKVKDFGLPVILLGTEKNSVLPIGRIPSITLFSELVNSEGSVSLDSNRNGIKQNDTAVLLYSSGTTGTSKGVILSHRNFIAASLMVTADQELAGEMNNIFLCVLPMFHVFGLAVIMFSQLQRGNAIVSMSKFDLEMILKTVEKYRITHMWVVPPIILGLAKSSMVKKYNLSSLKQIGSGAAPLGRELMQECAKNFPQAVVVQGYGMTETCGIVSIENPMPRHXXXXXHSGSAGTLAPGVEGQIVSVDKLKPLPPGQLGEIWVRGPNMMQGYFNNPQATKLTIDKQGWVHTGDLGYFDDEGQLYVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPIAYVVRAPNSSLTEEDVKKFIADQVAPFKRLRRVTFINSVPKSASGKILRRELIDKVRSKL
>rna-XM_011100428.2
MGTDAQNLKQEEIIFRSKYPPVQVPDDVTLPEFVLSNVELYQDKVAFVDSVTGKGCTYGEVSRDVKRFSRALRSLGLRKGRVVVVLLPNVPVYATIALGIMAAGGIFSGANPSAHASEIKKQAEAADAKLVVTDGSTYHKVKDLGLPVIIHGEDRVEGTIYWDELLEAADKASADTTDDKVQQTDICALPFSSGTTGLSKGVMLTHRNLVANLCSSLFSVGPELVGQITILGLIPFFHIYGLTGICCATIRNKGKVVVMRRYELRAFLKALITHQVTFAPIVPPIVLGLVKNPIVDEFDLSKLRLRSIMTAAAPLAPEILNEFEKKFPGVEVQEAYGMTEHSCITLTHGDPNKGHGIAKKNSVGFILPNLEVKFVDPESGKSLPKNTPGEICVRSQCVMKGYYKNEHETTLTIDKDGWLHTGDIGYIDDDEDVFIVDRIKELIKYKGFQVAPAELEAILLSHPSVEDAAVVGIPDDEAGEIPAACVVMNNKAKESEEDMMGYVSSNVASYKRVRVLQFVDAIPKSPSGKIMRRLIKENMVKTL
MATATKQKDIIFRSKLPDIYIPNHLPLHSYCFQNISQFSTRPCLINGSTDDVYTYEEVELVSRRVAAGLSKLGIRKGDTIMILLPNSPEFVFAFLGASYIGAVSTTANPFFTPAEVAKQAKASIAKLIITQACYVEKVREYGRENGVKVVCVDTPPAGSGCLEFSQLTSADKKEMPAVEIKPEDTVALPYSSGTTGLPKGVMLTHKGLVTNVAQHVDGENPNLYIHSEDVVLCLLPLFHIYSLSVMLCGLRVGAAILIMQKFDIVPLLELIQKYKVTIGPFVPPIVLDIAKSPVVGKYDLSSVRTVMSGAAPLGKELEDAVRIKFPNAKLGQGYGMTEAGAVLAMCLAFAKEPFEIKSGACGTVVRNAEMKILDPETGASLPRNQPGEICIRGDQIMKGYLNDPEATERTIDKEGWLHTGDIGFIDDDDELFIVDRLKEIIKYKGFQVAPAELEALLLNHPYIADAAVVPMKDEMKHEKTGEVPVAFVVKSKGSTMSEDEIKEFISKQVIFYKRIKRVFFMEAIPKSPSGKILRKDLRARLPAFSN
>rna-XM_011071601.2
MELEEHIFRSKLPDIYIPNHLPTHVYCFENLSNHRLRPALINGPTGEVFTHADVELTARRVAVGLHNLGIRKNHVIMLLLHNSPEFAFAFLASSFVGAAATTANPLYTAAEITLQAKISKPKLIITHACYVGKVEHFAFEEGAKIVTIDPPPSPLIIHLSELTRSDEKLLPEVEIQAEDMPALPFSSGTTGFPKGVMLSHKNLVTCVSQQVDGENPAFHLDVKDLTVCVLPLFHVYSLITVLLCSLRAGAAVLILPKYEINALMELIQKYRVTIAPFVPPILLAIAKIPAAAAGKFDLSSVRRVTCGAAPMDKQLEGAVKCKLPNAMIGQGYGMTEAGVLTMCLGFAKRPFRFKPGSCGTVIRNARMKVIDPSTGVSLPRNQTGEICIRGDAVMKGYYNEPEATKRTVDKEGWLHTGDIGYVDDDDEVFIVDRLKELIKYKGFHIAPAELEALLIAHPSISDAAVVPMRDEGAGEVPVAFVVPANGSSITQQEVKQYISKQVVSYKRINRVFFIDEIPKAPSGKILRKKLRARI
>rna-XM_011074951.2
MEPVTKQDDVVFRSKLPDIYIPKHLPLHSYCFENMPKFSSRPCLINGATDEVYTYEEVELTSRKVXXXXXXGDTIMLLLPNSPEFVFAFLGASYIGAISTMANPFFTPGEVIKQAKASNAKLIITQACYVEKVRDYASEKGVKVMCVDAPPSDCLKFSELTLADERDMPAVKIHPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHSEDVMLCVLPLFHIYSLNSVLLCGLRVGAAILIMQKFDIVPFLELIQKYRVTIGPFVPPIVLAIAKSPLVDKYDLSSVRTVMSGAAPLGKELEDAVRIKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDTETGQSLGRNQPGEICIRGDQIMKGYLNDPESTERTIDKEGWLHTGDIGFIDADDELFIVDRLKEIIKYKGFQVAPAELEALLLNHPYISDAAVVPMKDEQAGEVPVAFVVKSNGSNITEDEIKQFVSKQVVFYKRINRVFFIESIPKSPSGKILRKDLRARLAAGIPN
>rna-XM_011086311.2
MLSVASVETQNPELSSSLVLPQNQTSETHVFVSKLPAIPISNHLPLHTYCFENLSQYPDRSCLLVGSTGKSYSFAETHLVCRKVAAGLSNLGIRKGDVVMALLQNCAEFVFTFMGASMIGAVTTTANPFCTTKEIFKQFNASKSKVIITQSQYVDKLRDPGDSSLVFGEDFSVITIDSPPEGCLHFSVLSEANENEAPEVEIDPDDAVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNLYLKPDDVVLCVLPLFHIYSLNSVLLCSLRAGAPVLLMQKFEIGSLLELIQRHRVSVAAVVPPLVLALAKNPLVDNFDLSSIRMVLSGAAPLGKELEAALLSRVPQAVFGQGYGMTEAGPVLSMSPAFAKQPLPTKSGSCGNVVRNAELKVVDPETGCSLPRNHPGEICIRGPQIMKGYLNDAEATARTIDVDGWLHTGDIGYVDDDDDVFIVDRVKELIKFKGFQVPPAELEALLISHPNIADAAVVPQKDEAAGEVPVAFVVRSNGFELTEEAVKEFISKQVVFYKRLHKVYFVHAIPKSPAGKILRKDLRAKLAAAAPSSTS
>rna-XM_011088970.2
MKLKTCMHVMNMLTGSFTARFSSTSAAGHFSARNRSWFLFQPPACAFQNKLRICMMPLKYHVSTFNFRAMQTETTPTPLLYSEDGIHRSPRPPIFLPNLSMISFLFRKLPSNAHSPALIQAETGQTLTFSDLKTQVFNFSKTLLDFNISKNDVVLIISPNSLLFPVAIFAVVAVGAIATTANPLCTAAEISKQVKDSNPKLIITTPQLHDKIKHLNLPCIMLATSKIPIYSSTTSSNSTWYYSHSDTFSSDIALPPVMQTDVAAILYSSGTTGTSKGVVLTHRNFIASALMMTSDQESYGDSRNVFLCFLPMFHIFGLSALLYAQLQRGNTVVVMARHEMKKMLSAVEKYKVTHLWVVPPVVVELAKHQEMVKEYDISSVREILSGAAPLGKETAEECARIFPDAVVYQGYGMTETGGPISFGNVRTDTPYSGSTGVLAPGVEAQIVNLGTMKPLPPLRRGEIWVRGLMVMQGYFNNQKATMETIDEQGWLHTGDIGYFDEKGRLYVVDRVKELIKCNGYQVAPAELEELLLTHPEIKDAAVIGLADAEVGEVPIAYVVRSSTTSLVEEEVKTFIAEQVAAYKRLRRVIFTDSIPKSASGKILRKELAQRFLSKL
>rna-XM_011088853.2
MPSQLIYGNDGIYRSPRPPLSLPQDPKFSMIPYLFRNLSSISHLPALVDAETGQTSTFSVLRTQVLNFSKALLDLSVSKNDVVLIISPNSLLFPVAFFAVVAIGAIATTANPLYTAAEISKQVKDSDPKLIITIPPLYDKIKHLNLPCIMLTNSTTPSNSNWYNSSDFINKTSLNVLLSDSDFPPVHQDDPAAILYSSGTTGASKGVVLSHKNFIATSMMVTSDQDQAYGEAKNVFLCFLPMFHISGLVAVLFAQLQRGNKVVVMPRYEMEKMLRTIEKYKVSHFFAAPPVIVALAKNQEVVKKYDVSSLREIGSGAAPLGKDVLEECAKVFPQTALYQGYGLTETCGAVSLENAAASSQHSGSTGMLDPGVEARIMDLERMQPLPPLQKGEIWVRGPNVMLGYFKNEKATKETIDDEGWLHTGDLGYFDNEGRIHVVDRLKELIKYKGFQVAPAELEELLLTHPEIKDAAVIGLSDVDAGEVPIAFVVRSSYSSLTEVETKDFIAKQVAPYKRLRKVIFSEEIPKSAAGKILRRELRHRFLSKL
>rna-XM_011090937.2
MEKSGYGRDGVYRSLRPPLFLPKDPNLSMVSFLFRNASSFADKPALIDSHTGKILTFAQFKSMVSRVSHGLLQLGIKKNDIVLIYAPNSIQYPLCFFGIVAIGAVATTVNPIYTVSELSKQVQDSKAKLIITVEDLLPKVKDFGLPVILLGTEKNSVLPIGRIPSITLFSELVNSEGSVSLDSNRNGIKQNDTAVLLYSSGTTGTSKGVILSHRNFIAASLMVTADQELAGEMNNIFLCVLPMFHVFGLAVIMFSQLQRGNAIVSMSKFDLEMILKTVEKYRITHMWVVPPIILGLAKSSMVKKYNLSSLKQIGSGAAPLGRELMQECAKNFPQAVVVQGYGMTETCGIVSIENPMPRHXXXXXHSGSAGTLAPGVEGQIVSVDKLKPLPPGQLGEIWVRGPNMMQGYFNNPQATKLTIDKQGWVHTGDLGYFDDEGQLYVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPIAYVVRAPNSSLTEEDVKKFIADQVAPFKRLRRVTFINSVPKSASGKILRRELIDKVRSKL
>rna-XM_011100428.2
MGTDAQNLKQEEIIFRSKYPPVQVPDDVTLPEFVLSNVELYQDKVAFVDSVTGKGCTYGEVSRDVKRFSRALRSLGLRKGRVVVVLLPNVPVYATIALGIMAAGGIFSGANPSAHASEIKKQAEAADAKLVVTDGSTYHKVKDLGLPVIIHGEDRVEGTIYWDELLEAADKASADTTDDKVQQTDICALPFSSGTTGLSKGVMLTHRNLVANLCSSLFSVGPELVGQITILGLIPFFHIYGLTGICCATIRNKGKVVVMRRYELRAFLKALITHQVTFAPIVPPIVLGLVKNPIVDEFDLSKLRLRSIMTAAAPLAPEILNEFEKKFPGVEVQEAYGMTEHSCITLTHGDPNKGHGIAKKNSVGFILPNLEVKFVDPESGKSLPKNTPGEICVRSQCVMKGYYKNEHETTLTIDKDGWLHTGDIGYIDDDEDVFIVDRIKELIKYKGFQVAPAELEAILLSHPSVEDAAVVGIPDDEAGEIPAACVVMNNKAKESEEDMMGYVSSNVASYKRVRVLQFVDAIPKSPSGKIMRRLIKENMVKTL
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University