Enzyme
Found in hops (Humulus lupulus). The enzyme can also methylate xanthogalenol.
OMT
Enzyme
Xanthohumol 4-O-methyltransferase
Enzyme name
EC:2.1.1.338
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:desmethylxanthohumol 6'-O-methyltransferase
Sysname
S-adenosyl-L-methionine + desmethylxanthohumol = S-adenosyl-L-homocysteine + xanthohumol [RN:R08004]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];xanthohumol [CPD:C16417]
Product
Species information
Primula vulgaris
Species name
Primula vulgaris is a species of eudicot in the family Primulaceae (primrose family).
Species info
Gene sequence info
Primula_vulgaris.OMT.fa
Download
>mRNA28038
MGENENTCAELLKAQAHIYGQTHSYINSAALKCAVQLGIPDVIHNHGKPMTIPELAAALPINQAKAHFLRHLMRVLVNSGIFAQENDNEDDTGYILTPSSRLLLDTPLSARKLVIVNLDPRTLKPWENLGAWFKNGDATPFYTTYGVGSWEFAAKNSDLGTSINELMAEDSRLTEKALLNECKGVFEGLTSLLDVAGGTGTMARAITKVFPNLKCIVFDQPHVVANCEGNEKVEFIGGDMFEMIPSANAILLKMILHNWSDEACVTILKKCREAVPSKDKGGKVIVIDIAMENNRGEDNTTFEAQSFYDMKMMVILDGKERNKREWAKLFSEAGFSHHKITPLGGLKSVIEAYP
>mRNA28924
MGKVNEESTCSELLQAQAQIWNQTHSYMKSATLKCAVQLGIPDTIHSHGKPMTLSELAQTLPINQAKAHSLRHLMRVLVNSGFFTQEKAITGEKEGDDDDEDTTYALTPASKLFLKDNPLTASTFMLVNLDPRILKPWQFLGDWFLNNDRTPFDTAFGTGLWDYVEKDPVLGSRFNELMAEDSRLISKVLMKECKGVFEGLTSLVDIAGGTGTTARAIAQALPNLKCIVLDLPHVVANLTGSENLEFIGGDMFQAIPTANAILLKWILHNWSDEDCVKILKKCKEAIPSKENGGKVIIIDIAMENKRSDDNEAFEAQSFFDMLMVVLFGSKERTKKEWAKLLSDAGFSNYKVTPLLGLRSIIEAYP
>mRNA28923
MSKLNEESSCSELLQAQAQIWHQTLSFIKSATLKCAVELGIPDVIHNHGKPMTLPELAQKLPINQVKAHFLDNLMRVLVNSGFITQEKALTEEEKEEYDDDDNATYALTPASRLFLKDYPFSARAFMLVNLDPRILKPWQFLGDWFLNDDDRSLFDTAYETGLWAYSEKDPIFGRHFSEVMAEDSRLISEVLMKECKGVFEGLTSLVDIAGGTGTTARAIAQTLPNLKCIVLDLPHVVANLNGSENLEFVGGDMFQAIPTANAILLKWILHNWSDEDCVKILKKCKEAIPSKENGGKVIIIDIVMENKRSDDNEAFEAQSFFDMLMVMLFGSKERTMKEWAKLLSDAGFSNYKSAPPPSPSGPVNITAILTKGGQYSTLIRLLTSTQAADQINGQVNNSRDGMTVFAPTDTAFMNLPAGYMNNLSTQQQVQLVQYHVLPKYYAKSDLLTVPNPVRTQASGQDGKVFGLYFSGEGNQVNVSSGLVVTQVNNALREESPLSVYQMDKVLLPKEFTEATPPSPSPVTEKTPADSSSGGKAKSEAGSPPSASTRLDMRFDMVAVIGLFCVGLLS
>mRNA4050
MDLANIGKESEMLYSQAHIWNCIFNFINSASLKCAVQLGIPDIVHKHGKPITLSELNACLPINQAKAQNILRLMNLLVHFGFFTKERVLVENKLEEDGYLLAPASRLLLEDEPLNVRPFLLTILDPVLTKPCDYVSEWFQNEDLTPFNTAHGKGIWEYGAEESRFGGLFNDAMASDARLVISVVLKKCRDVFMGMNSLVDVGGGTGTVAKSIADAFPELKCTVFDLPHVVSGLEGSNNLRFVGGDMFVEIPPSDAVMLKWILHDWSDEESVKILKKCKEAIPSKEKGGKVIIIDMTVDNKKGSDAEFTETQLLVDMMMMTLYTGKERNETEWAKLFSDAGFSDYKITPVLGLRSLIEWILHDWSDEDSVKILKKCKEAIPSKEKGGKVIIIDMKVDNKKGSDAEFTETQLLFDMLMMILVTGRERNETEWAKLFSYPGFSDYKISPVLGLRSLIETYP
>mRNA7067
MALKSAVELRIPDIIHSHSQPVTLGEIISFIDSPSPDITSLGRLMRLLVHRKIFTANPGSDGGETVYGPTHRSSWLLHDTEFSLAPMLAMENNKVMLGSWLHLSDCVREGGPAFNKLHGLEFWEYGSQNPAFSRIFNNAMECTAKIILQAMECTAKIILQAILEGYKDGFDLVGSMVDVGGGTGAAIAAIVEANPQISRINFDQPHVIATAPEYNGVTHIGGDMFITIPKADAIFMKWILHDWSDEDCPDKLS
>mRNA8667
MDLANIGKESEILYSQAHIWNCIFNFINSASLKCAVQLGIPDIVHKHGKPITLSELNACLPINQAKAQNILRLMNLLVHFEFFTKERVLVENKLEEDGYLLAPASRLLLEDEPLNVRPFLLAMLDPVLTKPWDYMSEWFQNEDLTPFNTAHGKGFWEYGAEESRLGGFFNDAMASDARLVISVVLKKGRDVFMGLNSLVDVGGGTGTVAKSIADAFPELKCTVFDLPHVVSGLEGSNNLRFVGGDMFVEIPPSDAVMLKWILHDWSDEESVKILKKCKEAIPSKEKGGKVIIIDMKVDNKKGSDAEFTETQLLFDMLMMILVTGKERNETEWAKLFSDAGFSDYKITPVLGLRSLIEVYP
>mRNA21167
MECDLLEAQAHIWNHTFSFIKSEALKSAVQLGIPDIIHNHGQPMTLHQLVTALQVNPTKANFVHRLMSTLAHSGFFTIEEQVSGNDDEIWYNLTPTSHLLIKDDPFSVSPFLLSMLDPALVNPWQNLTTWLKNDETTLFCTENKRTFWEQLGKEKGFGDGFNEGMASDARLVANVLVSKCKFIFEGLDSLVDVGGGTGTVARTVANAFPNMTCTVFDLPRVVDGLVGNGNLKFIGGDLFEAIPPADAILLKWMFHAWGDEDCIKILKKCKEAMNSTKGAKLIVIEMVVDTKKRDDKSAETQLLFDMVMMGCVAGIERNENQWAKIFSDAGFSGYKIFPLLARGLGDFSEKRLHSFKEREERLAGRSVLAGNSMLAGRGVIAERSVLAGRNVLTRRSVLVGKSVLEGRSVLAWRRVLAVGAVLAWKSVLAGRNMLARRSVLLTSLVSSLGQILNDPLNFS
MGENENTCAELLKAQAHIYGQTHSYINSAALKCAVQLGIPDVIHNHGKPMTIPELAAALPINQAKAHFLRHLMRVLVNSGIFAQENDNEDDTGYILTPSSRLLLDTPLSARKLVIVNLDPRTLKPWENLGAWFKNGDATPFYTTYGVGSWEFAAKNSDLGTSINELMAEDSRLTEKALLNECKGVFEGLTSLLDVAGGTGTMARAITKVFPNLKCIVFDQPHVVANCEGNEKVEFIGGDMFEMIPSANAILLKMILHNWSDEACVTILKKCREAVPSKDKGGKVIVIDIAMENNRGEDNTTFEAQSFYDMKMMVILDGKERNKREWAKLFSEAGFSHHKITPLGGLKSVIEAYP
>mRNA28924
MGKVNEESTCSELLQAQAQIWNQTHSYMKSATLKCAVQLGIPDTIHSHGKPMTLSELAQTLPINQAKAHSLRHLMRVLVNSGFFTQEKAITGEKEGDDDDEDTTYALTPASKLFLKDNPLTASTFMLVNLDPRILKPWQFLGDWFLNNDRTPFDTAFGTGLWDYVEKDPVLGSRFNELMAEDSRLISKVLMKECKGVFEGLTSLVDIAGGTGTTARAIAQALPNLKCIVLDLPHVVANLTGSENLEFIGGDMFQAIPTANAILLKWILHNWSDEDCVKILKKCKEAIPSKENGGKVIIIDIAMENKRSDDNEAFEAQSFFDMLMVVLFGSKERTKKEWAKLLSDAGFSNYKVTPLLGLRSIIEAYP
>mRNA28923
MSKLNEESSCSELLQAQAQIWHQTLSFIKSATLKCAVELGIPDVIHNHGKPMTLPELAQKLPINQVKAHFLDNLMRVLVNSGFITQEKALTEEEKEEYDDDDNATYALTPASRLFLKDYPFSARAFMLVNLDPRILKPWQFLGDWFLNDDDRSLFDTAYETGLWAYSEKDPIFGRHFSEVMAEDSRLISEVLMKECKGVFEGLTSLVDIAGGTGTTARAIAQTLPNLKCIVLDLPHVVANLNGSENLEFVGGDMFQAIPTANAILLKWILHNWSDEDCVKILKKCKEAIPSKENGGKVIIIDIVMENKRSDDNEAFEAQSFFDMLMVMLFGSKERTMKEWAKLLSDAGFSNYKSAPPPSPSGPVNITAILTKGGQYSTLIRLLTSTQAADQINGQVNNSRDGMTVFAPTDTAFMNLPAGYMNNLSTQQQVQLVQYHVLPKYYAKSDLLTVPNPVRTQASGQDGKVFGLYFSGEGNQVNVSSGLVVTQVNNALREESPLSVYQMDKVLLPKEFTEATPPSPSPVTEKTPADSSSGGKAKSEAGSPPSASTRLDMRFDMVAVIGLFCVGLLS
>mRNA4050
MDLANIGKESEMLYSQAHIWNCIFNFINSASLKCAVQLGIPDIVHKHGKPITLSELNACLPINQAKAQNILRLMNLLVHFGFFTKERVLVENKLEEDGYLLAPASRLLLEDEPLNVRPFLLTILDPVLTKPCDYVSEWFQNEDLTPFNTAHGKGIWEYGAEESRFGGLFNDAMASDARLVISVVLKKCRDVFMGMNSLVDVGGGTGTVAKSIADAFPELKCTVFDLPHVVSGLEGSNNLRFVGGDMFVEIPPSDAVMLKWILHDWSDEESVKILKKCKEAIPSKEKGGKVIIIDMTVDNKKGSDAEFTETQLLVDMMMMTLYTGKERNETEWAKLFSDAGFSDYKITPVLGLRSLIEWILHDWSDEDSVKILKKCKEAIPSKEKGGKVIIIDMKVDNKKGSDAEFTETQLLFDMLMMILVTGRERNETEWAKLFSYPGFSDYKISPVLGLRSLIETYP
>mRNA7067
MALKSAVELRIPDIIHSHSQPVTLGEIISFIDSPSPDITSLGRLMRLLVHRKIFTANPGSDGGETVYGPTHRSSWLLHDTEFSLAPMLAMENNKVMLGSWLHLSDCVREGGPAFNKLHGLEFWEYGSQNPAFSRIFNNAMECTAKIILQAMECTAKIILQAILEGYKDGFDLVGSMVDVGGGTGAAIAAIVEANPQISRINFDQPHVIATAPEYNGVTHIGGDMFITIPKADAIFMKWILHDWSDEDCPDKLS
>mRNA8667
MDLANIGKESEILYSQAHIWNCIFNFINSASLKCAVQLGIPDIVHKHGKPITLSELNACLPINQAKAQNILRLMNLLVHFEFFTKERVLVENKLEEDGYLLAPASRLLLEDEPLNVRPFLLAMLDPVLTKPWDYMSEWFQNEDLTPFNTAHGKGFWEYGAEESRLGGFFNDAMASDARLVISVVLKKGRDVFMGLNSLVDVGGGTGTVAKSIADAFPELKCTVFDLPHVVSGLEGSNNLRFVGGDMFVEIPPSDAVMLKWILHDWSDEESVKILKKCKEAIPSKEKGGKVIIIDMKVDNKKGSDAEFTETQLLFDMLMMILVTGKERNETEWAKLFSDAGFSDYKITPVLGLRSLIEVYP
>mRNA21167
MECDLLEAQAHIWNHTFSFIKSEALKSAVQLGIPDIIHNHGQPMTLHQLVTALQVNPTKANFVHRLMSTLAHSGFFTIEEQVSGNDDEIWYNLTPTSHLLIKDDPFSVSPFLLSMLDPALVNPWQNLTTWLKNDETTLFCTENKRTFWEQLGKEKGFGDGFNEGMASDARLVANVLVSKCKFIFEGLDSLVDVGGGTGTVARTVANAFPNMTCTVFDLPRVVDGLVGNGNLKFIGGDLFEAIPPADAILLKWMFHAWGDEDCIKILKKCKEAMNSTKGAKLIVIEMVVDTKKRDDKSAETQLLFDMVMMGCVAGIERNENQWAKIFSDAGFSGYKIFPLLARGLGDFSEKRLHSFKEREERLAGRSVLAGNSMLAGRGVIAERSVLAGRNVLTRRSVLVGKSVLEGRSVLAWRRVLAVGAVLAWKSVLAGRNMLARRSVLLTSLVSSLGQILNDPLNFS
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University